DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment sip1 and zgpa-1

DIOPT Version :9

Sequence 1:	NP_001285636.1	Gene:	sip1 / 44238	FlyBaseID:	FBgn0024191	Length:	839	Species:	Drosophila melanogaster
Sequence 2:	NP_501296.1	Gene:	zgpa-1 / 177568	WormBaseID:	WBGene00016383	Length:	432	Species:	Caenorhabditis elegans

Alignment Length:	362	Identity:	70/362 - (19%)
Similarity:	126/362 - (34%)	Gaps:	144/362 - (39%)

- Green bases have known domain annotations that are detailed below.

  Fly    70 VNFVAGGIQQAGKKKKKALQADDEKGSQKEGAEADQGEESDDSAASGRPAFGQNDPGSSNSSSEE 134
            |..:..||:.:.|:|......:.|:.:::|                          .||.|..|.
Worm   192 VKVLKSGIEISSKRKDLVPIGEVEEPTKQE--------------------------QSSESWKEL 230

  Fly   135 ERPTLSRKQPSTTFQHRSHIASERNVGAWEQHTRGIGAKLLLQMGYEPGKGLGKDLQGISHPVQA 199
            ::.||..             .:..::|.|  :..|:|.||:::|||:.|:||||...||.|.:||
Worm   231 KQETLGN-------------VTVGDLGKW--NGGGVGMKLMMKMGYKVGEGLGKRSDGIVHAIQA 280

  Fly   200 HVRKGRGAIGAYGPETAASIGGKTNKSIKVDEDVREAKEFKDQLNKWRKGSAGGAEPMERQGKRY 264
            .:.|                     |:..:||.:...::|.|:            :.:::.....
Worm   281 RICK---------------------KNASLDEVMTRKRKFIDR------------KEVQKNKNIK 312

  Fly   265 YYKSVEE----VIAKGHTSGHLLSEKLSKKLGNVRVIDMTGPEKRVLSGYHA--LGQAKITPEET 323
            ..|:.:|    :.|       .::.||.||  |.|.......|.:.::||.:  ||...:
Worm   313 KLKTTDESEMDIFA-------FINRKLEKK--NERTFADVRKETQEMAGYSSKTLGAKNL----- 363

  Fly   324 LYDTEATEKGSAPACVFAMPELTHNLQLLVSQCEQQIIAIDNQERECSSQQAALESEHRKLEEIV 388
                                    :|:|.:.|                     |:.:..||:..:
Worm   364 ------------------------DLELELKQ---------------------LKEKQNKLKSGI 383

  Fly   389 QLER---NHIRTLEESLERVERLID--NPDLSLPQAE 420
            |..|   |.:..:.|||..|:..|:  |..|:..|:|
Worm   384 QRNRGDKNTVSKMSESLREVDAKIESINRKLNRIQSE 420

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
sip1	NP_001285636.1	TIP_N	3..93	CDD:289242	5/22 (23%)
		G-patch	167..211	CDD:279867	18/43 (42%)
		GCFC	416..685	CDD:285127	2/5 (40%)
zgpa-1	NP_501296.1	ZnF_C3H1	121..144	CDD:214632
		G-patch	249..289	CDD:279867	19/60 (32%)
		NAT_SF	<254..>421	CDD:302625	53/259 (20%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1238995at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010