Protein Alignment sip1 and tfip11

DIOPT Version :9

• Sequence 1: NP_001285636.1
• Gene: sip1 / 44238
• FlyBaseID: FBgn0024191
• Length: 839
• Species: Drosophila melanogaster
• Sequence 2: NP_001090845.1
• Gene: tfip11 / 100038256
• XenbaseID: XB-GENE-984521
• Length: 825
• Species: Xenopus tropicalis
• Alignment Length: 866
• Identity: 308/866 - (35%)
• Similarity: 459/866 - (53%)
• Gaps: 92/866 - (10%)

  Fly     5 DYERFEITDYDLDNEFNINRPRGRQSRHQQIYGIWAD-DSEEESGGEGGTKRRGRAARKPKDYTM 68
            :.|.|||||:||.||||.||.:..|::.:..||:||: ||::|....||        ::.:||:.
 Frog    17 EMENFEITDWDLQNEFNPNRRKHFQTKEEATYGMWAERDSDDERPSFGG--------KRSRDYSA 73

  Fly    69 PVNFVAGGIQQAGKKKKKALQADDEKGSQKEGAEADQGEESDDSAASGRPAFGQNDPGSSNSSSE 133
            ||||::.||                   :|..||.....:||....:.|..|.::.......:..
 Frog    74 PVNFISAGI-------------------RKPAAEEKSDSDSDSETQARRETFPKDFEAKKLRTGG 119

  Fly   134 EERPTLSRKQPSTTFQHRSHIASERNVGAWEQHTRGIGAKLLLQMGYEPGKGLGKDLQGISHPVQ 198
            ..:|:      ..||  ...|.|..:.|:||:||:|||.|||.:|||..|:||||:.|||..|::
 Frog   120 NFKPS------QRTF--AGGIKSNTDFGSWERHTKGIGQKLLQKMGYVQGRGLGKNAQGIIAPIE 176

  Fly   199 AHVRKGRGAIGAYGPETAASIGGKTNKSIK----VDEDVREAKEFKDQLNKWRKGSAGGAEPMER 259
            |..|||:||:||||.|       :|.:|||    ||.:..|.|||:.::::|||...||     :
 Frog   177 AKQRKGKGAVGAYGSE-------RTKQSIKDFPVVDSEEEEEKEFQKEMSQWRKDPGGG-----K 229

  Fly   260 QGKRYYYKSVEEVIAKGHTSGHLLSEKLSKKLGNVRVIDMTGPEKRVLSGYHALGQAKITPEETL 324
            :..:|.||:|||:.|||.....|.:.:  |::..|:||||||.|::|...|..|......|.|..
 Frog   230 KKPKYSYKTVEELKAKGKVGKSLSAPQ--KEISQVKVIDMTGREQKVYYSYSQLAHKHNIPGEAP 292

  Fly   325 YDTEATEKGSAPACVFAMPELTHNLQLLVSQCEQQIIAIDNQERECSSQQAALESEHRKLEEIVQ 389
            ......||...    ||:|||.||||||:...||:||..|.|.:........|..|..||.|:::
 Frog   293 GQGAKEEKPQG----FALPELEHNLQLLIDMTEQEIIQNDRQLQYEQDMVVNLTHELEKLSEVLE 353

  Fly   390 LERNHIR-------TLEESLERVERLIDNPDLSLPQAERLFRELLVDYAAEFHEFGLADLAAGVI 447
            .|...|:       |:||...|::.:.||| |:|.:..|:|..|...|..|:.....|||:..::
 Frog   354 REEQAIQNLSKVLETVEECERRIQPMCDNP-LTLEECARIFEMLQDKYYEEYKMSEKADLSVAIV 417

  Fly   448 APLLKRELVQWQPLENPTEPLPLIKKWRGMLQQGDAAEQQPRNV-FDPYSSLIWAGVMPSFRSSA 511
            .||:|.....|.||.:||....::.||:.:|::|........:. .|||..|:|...:|..||..
 Frog   418 YPLMKDYFKDWNPLRDPTYGTDVMSKWKNLLEEGHLLSHSAHDASMDPYHRLLWETWVPLLRSII 482

  Fly   512 AAWQPKEHPPMASLLDAWAPLLPSWVLDSVLEQLVLPRLVAGVQEWDPLTDTVPIDSWVLPWHAI 576
            |.|||:...||...||.|..|||.|:||::|:||:.|:|...|:.|:||||||||.||:.||..:
 Frog   483 AQWQPRNCAPMVDFLDCWVHLLPVWILDNILDQLIFPKLQKEVENWNPLTDTVPIHSWIHPWLPL 547

  Fly   577 LGSKLEEAVYPQIRSKLGIALRAWSPHDRSARAMLTPWQKAFPEEEMQEFLQRYIVPKLQATLGE 641
            :.|:||....| ||:||..||:.|.|.|.||:.:|.||::.|.....:.|:.:.|:|||...|.|
 Frog   548 MQSRLEPLFSP-IRNKLANALQKWHPSDSSAKLILQPWKEVFTPGSWEAFMVKNILPKLGMCLSE 611

  Fly   642 LIINPMHQDLELWQQVWEWHELIDPMYMAQLLDRHFFPRWMQVLVVWLNQSPDYAEISRWYTGWK 706
            .:|||..|.:|::..|.:|..::....:..:|::||||:|:|||..||:.:|:|.||::||.|||
 Frog   612 FVINPHQQHMEVFHWVTDWEGMVSLSSIVGILEKHFFPKWLQVLCSWLSNTPNYEEITKWYLGWK 676

  Fly   707 SMLSEPLLREPSVKEHLRRALEIMHRASDTLLQPTVTPTPPPPVP-------------------- 751
            ||.|:.:|..|::|:....||:||:||..:.:...:.|.....:.
 Frog   677 SMFSDLVLAHPAIKDKFNEALDIMNRAVSSSVGAYMQPGARESIAYLTQTERRKDFQYEAMQERR 741

  Fly   752 PAPVIMMDLIHPPA--QLEFKELVSQQCADLGIIFAPLPGRREMGKQIYRVGKLFCYIDRHVCMV 814
            .|..|....|...|  .:.||:|:..:..:..|:|.||.|:|..|||:|...::..||||.|..|
 Frog   742 DAESIAQRGIGAAAAVPMNFKDLIQSKAEEHNIVFMPLIGKRHEGKQLYNFNRIVIYIDRGVVFV 806

  Fly   815 SDGSFSNWKPVSLNHLLERSQ 835
            .  ....|.|.||..|::.::
 Frog   807 Q--GEKTWVPTSLQSLIDMAK 825

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
sip1	NP_001285636.1	TIP_N	3..93	CDD:289242	32/88 (36%)
		G-patch	167..211	CDD:279867	26/43 (60%)
		GCFC	416..685	CDD:285127	103/269 (38%)
tfip11	NP_001090845.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..135		43/152 (28%)
		TIP_N	17..99	CDD:289242	37/108 (34%)
		G-patch	145..189	CDD:279867	26/43 (60%)
		GCFC	386..655	CDD:285127	103/269 (38%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	224	1.000	Domainoid score	I2501
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H40813
Inparanoid	1	1.050	526	1.000	Inparanoid score	I1214
OMA	1	1.010	-	-		QHG54857
OrthoDB	1	1.010	-	-		D1238995at2759
OrthoFinder	1	1.000	-	-		FOG0004443
OrthoInspector	1	1.000	-	-		oto104151
Panther	1	1.100	-	-	LDO	PTHR23329
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1931
SonicParanoid	1	1.000	-	-		X3147
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	12	12.110