DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment bon and AT2G27980

DIOPT Version :9

Sequence 1:	NP_001262765.1	Gene:	bon / 44235	FlyBaseID:	FBgn0023097	Length:	1207	Species:	Drosophila melanogaster
Sequence 2:	NP_180365.6	Gene:	AT2G27980 / 817342	AraportID:	AT2G27980	Length:	1072	Species:	Arabidopsis thaliana

Alignment Length:	968	Identity:	177/968 - (18%)
Similarity:	293/968 - (30%)	Gaps:	335/968 - (34%)

- Green bases have known domain annotations that are detailed below.

  Fly   137 EFIVDNQFLIEQCTAGDSGDGVGLLGLTGEGQKSSAAASIQCSSCSDGAVATSWCVD--CSEYIC 199
            :|::.:|  .|.|.....|...|...|.||.:......||:.|....|.....:..|  ..|.:.
plant    25 QFVLKSQ--SEICGGESLGRTRGSRNLNGESRSVEVKKSIRASGLKSGIKKMRFSKDEEVGEVVM 87

  Fly   200 DSCVQAHQRLKITKDHTI-------------KPKDEANNEQLAGAAGVDKLHMCQ---LHPQEKL 248
            ...|......:..|...|             |..:|.|:.::..  |.|.:.|.:   |...||:
plant    88 SDTVGVGLEEEEVKSDVIDVDSALVESMSEDKGLEEKNDVEIEN--GDDNVVMNEDHLLEQTEKV 150

  Fly   249 S-----------------------LFC----ETCDKLTCRDCQLSDHRDHKYKFAHEIATESRQA 286
            |                       :.|    ...:|:..|.|::...|...|....:..|.|...
plant   151 SEKVIEAEKVCSIGGDSVIDREIVVACPAGLSVMEKMASRSCKVKLERGLVYAKPCKRLTRSMLK 215

  Fly   287 LSTLVSEINY-------KRFLLSSATKVIDDRQQLIHDKKKDLIKEITAMAVKITNTVNTRGKQL 344
            :..:.||:|.       ::..:.|....:|....:.:..:::|:::..   |:|...:.:|..|
plant   216 VEGIKSEVNADDDHVNPEKDAIGSEDNCVDVSGSVAYVVEEELLEQNN---VEICLGLPSRSSQ- 276

  Fly   345 IMRLNEVCDSKLKVLVEKKETLQLLSDNTDHCIDFMQNALEKGSDFAILSS--KKSLVRHLQKLK 407
             |..:.:|             |.|.|.:      |..:...:|.|...::.  .|.|.|..:.|.
plant   277 -MNGHSLC-------------LGLPSRS------FQMSGHSQGVDKKAVNDTVDKPLRRFTRSLV 321

  Fly   408 CQRADIPNPEIPVRIQVQLNQVSDLQKVISQLGIIIVDGKPYPPTPSPNGTPQPQHPPRQPPSPN 472
            .|.:|..||.:.     ...:.:||..|......:.:||...|...:||...:|:...|     |
plant   322 KQESDSDNPNLG-----NTTEPADLVDVDMHANDVEMDGFQSPSVTTPNKRGRPKKFLR-----N 376

  Fly   473 MAPPLRPGLPPGMPAGLSPNGPPVNFGPQNGPPLYSNAAQQQFNNLSMSRSFPG--DGSGKVRFG 535
            ....|:.....|:..||.              ..|...|:.:   .:.:|...|  .|||.:.|.
plant   377 FPAKLKDIFDCGILEGLI--------------VYYVRGAKVR---EAGTRGLKGVIKGSGVLCFC 424

  Fly   536 G-------MPPVGMQRHGQPHVSSSTHPQ-----NMDISLRGLLNNQAAQSPNAH---------- 578
            .       :.|...:.|..   |::..|.     ....:||.:: |...::|.|.
plant   425 SACIGIQVVSPAMFELHAS---SNNKRPPEYILLESGFTLRDVM-NACKENPLATLEEKLRVVVG 485

  Fly   579 ---------MAFNGPPSYPGGPQ-----------------GAPAPAHQPMGPQMRPHFMPGQQGF 617
                     ::..||...|...:                 .:|:.|:..:....||...|
plant   486 PILKKSSLCLSCQGPMIEPCDTKSLVVCKSCLESKEPEFHNSPSKANDALNGSSRPSVDP----- 545

  Fly   618 SQGGGPGGGPRDANFMNSNARFQSQYQRMANHAQQAAAAAAMAGAAGGGGGQIPSPGALQRPQMM 682
                            .|..|......|.:|..:|....:.             .||.:  |..:
plant   546 ----------------KSILRRSKSSPRQSNRREQPTRKST-------------EPGVV--PGTI 579

  Fly   683 SNPMQNVSAMQNSLGFHGSQAGFNTGPPQTSPQLGGGGMHSLAKWHIPQSAQQSNMCSQQGPLLP 747
            .:..:|.|...||   ||.         .|...|   .:|.|.               .:..:||
plant   580 LSESKNSSIKSNS---HGK---------LTRKDL---RLHKLV---------------FEDDILP 614

  Fly   748 -------FANGRQTSENFKISLKSPNTLKNSTPPSLGGGGAGHQGHGNGSSSAQLNAAALGLGPA 805
                   |..|.:....:|                        :|.|...|...
plant   615 DGTEVGYFVAGEKMLVGYK------------------------KGFGIHCSCCN----------- 644

  Fly   806 VSILSNVTSTNPKTPSPST---HENTKDFTEPIDKVRDDSINDLIATIAKLDSNGVQVLPEGRTK 867
                        |..||||   |.......:|...:              ..:|||
plant   645 ------------KVVSPSTFEAHAGCASRRKPFQHI--------------YTTNGV--------- 674

  Fly   868 TTSPQVHS-STDLSNTQEVNNKNEQKDDPNEDWCAVCLDGGELMCCDKCPKVFHQNCHIPAISSL 931
                .:|. |..||..|..:...      |:|.|::|.|||||:|||.||:.:|:.|  .::.||
plant   675 ----SLHELSVALSMDQRFSIHE------NDDLCSICRDGGELVCCDTCPRSYHKVC--ASLPSL 727

  Fly   932 PDESESWQCLLCVNIKELTKTEGSEKS--SSGELSALE---------LRILQRICLEL 978
            |  ||.|.|..|||:.|..|...|..:  ::|.:..::         :||:.....||
plant   728 P--SERWSCKYCVNMVEREKFVDSNLNAIAAGRVQGVDAIAEITNRCIRIVSSFVTEL 783

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
bon	NP_001262765.1	zf-RING_5	82..130	CDD:291308
		BBOX	239..275	CDD:237988	11/65 (17%)
		BBC	284..409	CDD:128778	22/133 (17%)
		PHD_TIF1_like	899..943	CDD:277016	21/43 (49%)
		Bromo_tif1_like	963..1072	CDD:99934	4/25 (16%)
AT2G27980	NP_180365.6	Jas	384..453	CDD:374386	15/88 (17%)
		Jas	599..669	CDD:374386	18/148 (12%)
		PHD_SF	697..737	CDD:389947	21/43 (49%)
		PHD_SF	796..838	CDD:389947
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm3092
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.000