Protein Alignment bon and trim33

DIOPT Version :10

• Sequence 1: NP_001262765.1
• Gene: bon / 44235
• FlyBaseID: FBgn0023097
• Length: 1207
• Species: Drosophila melanogaster
• Sequence 2: NP_001002871.2
• Gene: trim33 / 324053
• ZFINID: ZDB-GENE-030131-2773
• Length: 1176
• Species: Danio rerio
• Alignment Length: 1222
• Identity: 324/1222 - (26%)
• Similarity: 489/1222 - (40%)
• Gaps: 288/1222 - (23%)

  Fly    18 GIKQEQ----LDAVPTDALPQMSTPNTASGAPTTSSLSSSS------------------------ 54
            |.|:.:    :|..|.:|..:..:..|...||||||.||||
Zfish    30 GAKEPEAVVSIDTEPKEAADEAKSQETVPQAPTTSSDSSSSGGGGEATDGTPNAESADPPPPPPP 94

  Fly    55 ---LSLSNPCDSA-----------------EKRSESNSSASAKFTLF-KCVYCAQLLGSND-RPK 97
               ...|.|.||.                 ...|.|:|:.:|...|. .|..|.|.|.:.| .||
Zfish    95 PPPPPPSTPADSTAAAASPAVVTEMSPPPPASTSSSSSTPAAPINLLDTCAVCKQSLQNRDCEPK 159

  Fly    98 LLECLHVACAQCVSTKFSEL----------DRSLPPLIHCPVCDNASQQEFIVDNQFLIEQCTAG 152
            ||.|||..|.:|:.....::          |..:..::.|.||....:|..:|||.|:.:
Zfish   160 LLPCLHSFCLKCIPQPDRKITMPVQGPHGQDTRIVNVMRCTVCHQDYKQIDMVDNYFVKD----- 219

  Fly   153 DSGDGVGLLGLTGEGQKSSAAASIQ-CSSCSDGAVATSWCVDCSEYICDSCVQAHQRLKITKDHT 216
                       |.|...:|...|.| |:||.|.|.|..:||:|.|::|.:|::||||:|.||||.
Zfish   220 -----------TSEATNTSVENSTQVCTSCEDNASAIGFCVECGEWLCKTCIEAHQRVKFTKDHK 273

  Fly   217 IKPKDEANNEQLAGAAGVDKLHMCQLHPQEKLSLFCETCDKLTCRDCQLSDHRDHKYKFAHEIAT 281
            |:.|:|.:.|.: |.:| .:...|.:|.||.|.|||||||.||||||||.:|::|:|:|..|...
Zfish   274 IRKKEEVSPESV-GTSG-QRPVFCPVHKQEALKLFCETCDTLTCRDCQLLEHKEHRYQFLDEACQ 336

  Fly   282 ESRQALSTLVSEINYKRFLLSSATKVIDDRQQLIHDKKKDLIKEITAMAVKITNTVNTRGKQLIM 346
            ..:..::|.::::..||.|:..:...:..|.:.:.:..|.:..||......:.|.:|.:||.|:.
Zfish   337 NQKGIIATFMTKLQEKRGLVEYSASEVQKRLKEVAETHKKVEHEIKIAVFTLINEINKKGKSLLQ 401

  Fly   347 RLNEVCDSKLKVLVEKKETLQLLSDNTDHCIDFMQNALEKGSDFAILSSKKSLVRHLQKLKCQRA 411
            :|..|...:...|:.::..:.:|:....|.::|...|:..||..|:|.||:.:...|:.:...|.
Zfish   402 QLESVTKDRSMKLLSQQRDISVLAQQIIHVLNFTNWAITNGSSTALLYSKRLITYQLRLIMKARV 466

  Fly   412 D-IPNPEIPVRIQVQLNQVSDLQKVISQLGIIIVDGKPYPPTPSPNG------TPQPQHPPRQPP 469
            | :|.....||.   ....:...|.:..||.:::: |..|..|..|.      :|...||.:...
Zfish   467 DAVPPANGAVRF---FCDPTFWAKNVVNLGNLVIE-KVAPTAPPSNMMVNQQISPGHNHPGKHSG 527

  Fly   470 SPNMAPPLRPGLPPGMPAGLSPNGPPVNFGPQNGPPLYSNAAQQQFNNLSMSRSFPGDGSGKVRF 534
            ..|:| .||  |.....|.::          |.....:.:..|||..:....:.
Zfish   528 QINLA-QLR--LQHMQQAAIA----------QKHQQQHQHHQQQQHQHQQQQQQ----------- 568

  Fly   535 GGMPPVGMQRHGQPHVSSSTHPQNMDISLRGLLNNQAAQSPNAHMAFNGPPSYPGGPQGAPAPAH 599
                ....|:..|.......|.|.:...:|  :.:|.:|.|.               ||||....
Zfish   569 ----QQQQQQQQQQQQQQQQHQQQIQQQMR--IASQMSQHPR---------------QGAPQMIQ 612

  Fly   600 QPMGPQMRPHFMPGQQGFSQGGGPGGGPRDANFMNSNARFQSQYQRMANHAQQAAAAAAMAGAAG 664
            ||      |..:...|...:||..|                |.:....:|.:..:|...|..|..
Zfish   613 QP------PPRLISMQALHRGGVNG----------------SSHMFPPHHLRMVSAQNRMPSAQP 655

  Fly   665 GGGGQIPSPGALQRPQMM---SNP----------MQNVSAMQNSLGFHGSQAG--FNTGP--PQT 712
            ...||   |..:.:||:.   |||          :.|:||...:.....|.|.  .:.||  |..
Zfish   656 RLNGQ---PYPMMQPQLQRQHSNPGHAGPFPVASLHNISAANPTSPTSASMANAHMHRGPSSPVI 717

  Fly   713 SP-QLGGGGMHSLAKWHIPQSAQQSNM-CSQQGPLLPFAN-GRQTSENFKISLKSPNTLKNSTP- 773
            :| :|            ||......|: |....|.:...: |..|.:|......|.|......|
Zfish   718 TPIEL------------IPSVTNPENLPCLPDIPPIQLEDAGSSTLDNILSRYISANAYPTVGPT 770

  Fly   774 -PSLGGG--GAGHQGHGN----------------GSSSAQLNAAALGLGPAVSILSNVTSTNPKT 819
             ||.|..  ..|..|..|                |||...::...:...|.|....:.|..|.||
Zfish   771 NPSPGPSTHSPGSSGLSNSHTPARPSSTSSTGSRGSSGTTVDQVKVKQEPGVEEECSYTGANVKT 835

  Fly   820 PSPSTHENTKD--------------FTEP---IDKVRDDSINDLIATIAKLDSNGVQVLPEGRTK 867
                  |.|||              .|.|   :..|...|:.|::.|:.:    .|:..|:....
Zfish   836 ------ERTKDGRRSACMMSSPEGSLTPPLPILGSVSTGSVQDILRTLGE----NVKSEPQSDNL 890

  Fly   868 TTSPQVHSSTDLSN-TQEVN--------NKNEQ-----KDDPNEDWCAVCLDGGELMCCDKCPKV 918
            ::....:|...|:| |...|        |.|.|     :|||||||||||.:||||:|||.||||
Zfish   891 SSCTNPNSRATLTNGTSGSNGGQRGGTTNANSQTTAGKEDDPNEDWCAVCQNGGELLCCDHCPKV 955

  Fly   919 FHQNCHIPAISSLPDESESWQCLLCVNI--KEL---------TKTEGSEKSSSGELSALELRILQ 972
            ||..||||.:.|.|  |..|.|..|.|:  .|:         ...|.:|.:.|.|    |.|..:
Zfish   956 FHITCHIPTLKSSP--SGDWMCTFCRNLANPEIEYNCDDDPPRNKEKNEMAMSPE----EQRRCE 1014

  Fly   973 RICLELYCQYEQSLNFREPESPANTSYYEIVSSPMSLDVIRTRLDPSSPNHYKDIAGFVSDVRLI 1037
            |:.|.::| :|.|..|:||...:..:||:|:..||.|.:::.:|....|.|||....|||||||:
Zfish  1015 RLLLHVFC-HELSTEFQEPVPTSVPNYYKIIKHPMDLTLVKRKLQRKHPLHYKSPKEFVSDVRLV 1078

  Fly  1038 FSNTYLF-----------------YQEDTKTYSNAKYLENFFEEQLAKWLPQ 1072
            |||...:                 .|.|::.....|.:..:|||:|.:..|:
Zfish  1079 FSNCAKYNEMSRIIQVYDEEKQSNVQADSEVAEAGKAVSLYFEERLLEIFPE 1130

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
bon	NP_001262765.1	RING_Ubox	<92..130	CDD:473075	12/48 (25%)
		Bbox1_TIF1	177..220	CDD:380863	23/43 (53%)
		Bbox2_TIF1_C-VI	238..278	CDD:380833	24/39 (62%)
		BBC	284..409	CDD:128778	27/124 (22%)
		Med15	486..>743	CDD:312941	51/275 (19%)
		PHD_TIF1_like	899..943	CDD:277016	27/43 (63%)
		Bromo_tif1_like	963..1072	CDD:99934	38/125 (30%)
trim33	NP_001002871.2	RING-HC_TIF1gamma	140..206	CDD:438422	19/65 (29%)
		Bbox1_TIF1g_C-VI	228..281	CDD:380905	26/52 (50%)
		Bbox2_TIF1g_C-VI	287..339	CDD:380888	26/52 (50%)
		BBC	338..464	CDD:128778	27/125 (22%)
		Amelogenin	<605..739	CDD:197891	38/170 (22%)
		TNG2	<836..982	CDD:227367	55/151 (36%)
		PHD_TIF1_like	936..978	CDD:277016	27/43 (63%)
		Bromo_tif1_like	1005..1130	CDD:99934	40/129 (31%)