Protein Alignment bon and mei-P26

DIOPT Version :10

• Sequence 1: NP_001262765.1
• Gene: bon / 44235
• FlyBaseID: FBgn0023097
• Length: 1207
• Species: Drosophila melanogaster
• Sequence 2: XP_061506762.1
• Gene: mei-P26 / 1273621
• VectorBaseID: AGAMI1_012843
• Length: 1092
• Species: Anopheles gambiae
• Alignment Length: 850
• Identity: 186/850 - (21%)
• Similarity: 292/850 - (34%)
• Gaps: 247/850 - (29%)

  Fly    15 LIAGIKQEQLDAVPTDALPQMS--TPNTASGAPTTSSLSSSS------------LSLSNPCDSAE 65
            |.|..:.:||       :|::.  :||.:|.:..::..|:||            |.|.|..:.|
Mosquito   122 LSASPRADQL-------VPKLGGPSPNNSSSSVCSNGSSTSSGMFPEVFKLDDMLELENVGNGA- 178

  Fly    66 KRSESNSSASAKFTLFK----------CVYCAQLLGSNDRPKLLECLHVACAQCVSTKFSE---- 116
              ...|.|....|.|..          |..|.....|   |::|.||||.|..|:....:|
Mosquito   179 --LSENGSTGGDFQLDNSSLSDLMEQDCTLCKNKFTS---PRVLSCLHVFCESCLDKLLAEGAGD 238

  Fly   117 --LDRSLPPLIHCPVCDNAS----------QQEFIVDNQFLIEQCTAGDSGDGVGLLGLTGEGQK 169
              ||......|.|.:|..|:          .|::|:.|                 :|.|:
Mosquito   239 KGLDGGNGGTIVCTICKQATPTGPKGAAGLHQDYILSN-----------------VLDLS----- 281

  Fly   170 SSAAASIQCSSCSDGAVATSWCVDCSEYICDSCVQAHQRLKITKDHTIKPKDEANNEQLAGAAGV 234
            :...|.:.|:||....:|.|.|.||:.::|.||..|||.::..:||  |....|:..:.|....:
Mosquito   282 TIEPALLACTSCKSKEMAISRCNDCANFLCASCEYAHQHMRCFEDH--KVVQLADLRKSAEKVAI 344

  Fly   235 DKLHMCQLHPQEKLSLFCETCDKLTCRDCQLSDHR--DHKYKFAHEIATESRQALSTLVSEINYK 297
            .|...|.:|..|.|..:|..|....|.:|.:.||:  :|.|....:.....||.|...:.|...|
Mosquito   345 HKPLYCPVHSMENLKYYCFNCQTPVCNECLIGDHKGSEHNYHIISDAEKPMRQELECSMREAKSK 409

  Fly   298 RFLLSSATKVIDDRQQLIHDKK-----------------KDLIKEITAMAVKITNTVNTRGKQLI 345
            ....:.||..::..   :||.:                 |.::::....|:|....:::..:..|
Mosquito   410 IEYCNQATSKLESS---LHDLQSQYETARGLINESYQSCKAVLEQCRENALKNLEKLHSERELKI 471

  Fly   346 MRL-NEVCDSKLKVLVEKKETLQLLSDNTDHCIDFMQNALEKGSDFAILSSKKSLVRHLQKLKCQ 409
            |.| :.|..|..|:.|..|               :.:..:::.:...:||.|..:...|.::
Mosquito   472 MDLYDNVAKSVEKIEVAAK---------------YARKVVDQANGPEMLSMKSMICAQLNQV--- 518

  Fly   410 RADIPNPEIPVRIQVQLNQVSDLQKVISQLGIIIVDGKPYPPTPSP---NGTPQPQHPPRQPPSP 471
            ....|..::...|:.|.| ....::::.:|     .||....:..|   |.|         .|||
Mosquito   519 MVTAPKVDVSFSIEFQSN-YEKFEQLVPEL-----FGKFRTESSLPVSVNET---------TPSP 568

  Fly   472 NMAPPLRPGLPPGMPAGLS-PNGPPVN--FGPQNGPPLYSNAAQQQFN-NLSMSRSFPGD----- 527
            .:         ||:|..:: .:..|||  .|...||...|..|....: ..||..||.||
Mosquito   569 TL---------PGVPIMVADAHHQPVNGGCGLSQGPLTASVTASSPISLPTSMQSSFDGDISTLG 624

  Fly   528 -------------GSGKVRFGGMPPVGMQRHGQPHVSSSTHPQNMDISLRGL----------LNN 569
                         .:|.....|.|.........|.|...|.|..   :|.||          |.|
Mosquito   625 TTYMLPNVLTPEPATGAANIAGPPNALSAGTPSPGVVVGTGPAT---TLPGLSSIAEYNLHRLAN 686

  Fly   570 QAAQSPNAHMAFNGPPSYPGGPQGAPAPAHQPMGPQMRPHFMPGQQGFSQGGGPGGGPRDANFMN 634
            .|.::.:..:..:..|.....|...||                        ||.......|:.::
Mosquito   687 LAGETASNDLTDSIVPVVNSNPTTGPA------------------------GGATPNFTLADLIS 727

  Fly   635 SNARFQSQYQRMANHAQQAAAAAAMAGAAGGGGGQIPSPGAL--QRPQMMSNPMQNVSAMQNSLG 697
            .|           .||.||.|..:|       |||..|.||:  ..|.:.|.||.:        .
Mosquito   728 GN-----------QHAIQALAKYSM-------GGQDMSNGAMLSAHPSLDSVPMMS--------D 766

  Fly   698 FHGSQAGFNTGP----PQTSPQLGGGGMHSLAKWHIPQSAQQSNMCSQQGPLLPFANGRQTSENF 758
            |.|...| :|.|    |...|.:.|.||:. |...:..|..|.:||         .|||..:...
Mosquito   767 FPGVLPG-STSPILPVPPNMPNIDGPGMNG-AGSDMAMSRFQPSMC---------VNGRTKATPM 820

  Fly   759 KISLK 763
            :|..|
Mosquito   821 QIRTK 825

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
bon	NP_001262765.1	RING_Ubox	<92..130	CDD:473075	14/43 (33%)
		Bbox1_TIF1	177..220	CDD:380863	17/42 (40%)
		Bbox2_TIF1_C-VI	238..278	CDD:380833	12/41 (29%)
		BBC	284..409	CDD:128778	24/142 (17%)
		Med15	486..>743	CDD:312941	67/294 (23%)
		PHD_TIF1_like	899..943	CDD:277016
		Bromo_tif1_like	963..1072	CDD:99934
mei-P26	XP_061506762.1	None