Protein Alignment bon and Trim28

DIOPT Version :9

• Sequence 1: NP_001262765.1
• Gene: bon / 44235
• FlyBaseID: FBgn0023097
• Length: 1207
• Species: Drosophila melanogaster
• Sequence 2: XP_006228170.1
• Gene: Trim28 / 116698
• RGDID: 620289
• Length: 861
• Species: Rattus norvegicus
• Alignment Length: 1114
• Identity: 262/1114 - (23%)
• Similarity: 397/1114 - (35%)
• Gaps: 369/1114 - (33%)

  Fly    26 AVPTDALPQMSTPNTASGA-------------PTTSSLSSSSLSLSNPCDSAEKRSESNSSASAK 77
            |..|.|....:..:.|||:             |..||.:::|.|.|:|         :.....|:
  Rat     6 AAATAAASAATAASAASGSPGSGEGSAGGEKRPAASSAAAASASASSP---------AGGGGEAQ 61

  Fly    78 FTLFKCVYCAQLLGSNDRPKLLECLHVACAQCVSTKFSELDRSLP---------------PLIHC 127
            ..|..|..|.:.|.....|:||.|||.||:.|       |..:.|               .::.|
  Rat    62 ELLEHCGVCRERLRPERDPRLLPCLHSACSAC-------LGPATPAAANNSGDGGSAGDGAMVDC 119

  Fly   128 PVCDNASQQEFIVDNQFLIEQCTAGDSGDGVGLLGLTGEGQKSSAAASIQCSSCSDGAVATSWCV 192
            |||......:.||:|.|:      .|||         .:....|..|:..|:||.|.|.|||:||
  Rat   120 PVCKQQCYSKDIVENYFM------RDSG---------SKASSDSQDANQCCTSCEDNAPATSYCV 169

  Fly   193 DCSEYICDSCVQAHQRLKITKDHTIKPKDEANNEQLAGAAGVDKLHMCQLHPQEKLSLFCETCDK 257
            :|||.:|::||:||||:|.|||||::....|....      .::...|.:|..|.|.||||:||.
  Rat   170 ECSEPLCETCVEAHQRVKYTKDHTVRSTGPAKTRD------GERTVYCNVHKHEPLVLFCESCDT 228

  Fly   258 LTCRDCQLSDHRDHKYKFAHEIATESRQALSTLVSEINYKRFLLSSATKVIDDRQQLIHDKKKDL 322
            ||||||||:.|:||:|:|..:.....|:.|::||..:..|...|...||.:....:.:.|.:|.:
  Rat   229 LTCRDCQLNAHKDHQYQFLEDAVRNQRKLLASLVKRLGDKHATLQKNTKEVRSSIRQVSDVQKRV 293

  Fly   323 IKEITAMAVKITNTVNTRGKQLIMRLNEVCDSKLKVLVEKKETLQLLSDNTDHCIDFMQNALEKG 387
            ..::....::|...:|.||:.|:....:|.:.:.:.|..:..|:..:..:.:|.:.|...|||..
  Rat   294 QVDVKMAILQIMKELNKRGRVLVNDAQKVTEGQQERLERQHWTMTKIQKHQEHILRFASWALESD 358

  Fly   388 SDFAILSSKKSLVRHLQKLKCQRADIPNPEIPVRIQVQLNQVSDLQKVISQLGIIIVDGKPYPPT 452
            ::.|:|.|||.:...|.:......|...|...::.|..||..:   |.....|.|:.:      .
  Rat   359 NNTALLLSKKLIYFQLHRALKMIVDPVEPHGEMKFQWDLNAWT---KSAEAFGKIVAE------R 414

  Fly   453 PSPNGT-PQPQHPPRQPPSPNMAPPLRPGLPPGMPAGLSPNGPPVNFGPQNGPPLYSNAAQQQFN 516
            |..|.| |.|..|||.|     .|..:.|.....|..:...   ..||..:.   || :|:...:
  Rat   415 PGTNSTGPGPMAPPRAP-----GPLSKQGSGSSQPMEVQEG---YGFGTDDP---YS-SAEPHVS 467

  Fly   517 NLSMSRSFPGDGSGKVRFGGMPPVGMQRHGQPHVSSSTHPQNMDISLRGLLNNQAAQSPNAHMAF 581
            .:..|||..|:.||.:|  .:|.|.::|              :|:.|      .:...|.....|
  Rat   468 GMKRSRSGEGEVSGLMR--KVPRVSLER--------------LDLDL------TSDSQPPVFKVF 510

  Fly   582 NGPPSYPGGPQGAPAPAHQPMGPQMRPHFMPGQQGFSQGGGPGGGPRDANFMNSNARFQSQYQRM 646
                                                     ||....|.|.:
  Rat   511 -----------------------------------------PGSTTEDYNLI------------- 521

  Fly   647 ANHAQQAAAAAAMAGAAGGGGGQIPSPGALQRPQMMSNPMQNVSAMQNSLGFHGSQAGFNTGP-- 709
               ..:..||||.||.|    |.:| |||...|     |:..::.::.    ..::|.....|
  Rat   522 ---VIERGAAAAAAGQA----GTVP-PGAPGAP-----PLPGMAIVKE----EETEAAIGAPPAA 569

  Fly   710 ---PQTSPQLGGGGMHSLAKWHIPQSAQQSNMCSQQGPLLPFANGRQTSENFKISLKSPNTLKNS 771
               |:|.|.|                     |...:|   |.|.|.:        |.||
  Rat   570 PEGPETKPVL---------------------MALTEG---PGAEGPR--------LASP------ 596

  Fly   772 TPPSLGGGGAGHQGHGNGSSSAQLNAAALGLGPAVSILSNVTSTNPKTPSPSTHENTKDFTEPID 836
                            :||:|:.|...|          ..|||.....|.
  Rat   597 ----------------SGSTSSGLEVVA----------PEVTSAPVSGPG--------------- 620

  Fly   837 KVRDDSINDLIATIAKLDSNGVQVLPEGRTKTTSPQVHSSTDLSNTQEVNNKNEQKDDPNEDWCA 901
             :.|||     |||                                                 |.
  Rat   621 -ILDDS-----ATI-------------------------------------------------CR 630

  Fly   902 VCLDGGELMCCDKCPKVFHQNCHIPAISSLPDESESWQCLLCVNIKELTKTEGS----EKSSSG- 961
            ||...|:|:.|::|...||.:||:|::..:|  .|.|.|.||..:.:|.:.:||    ...|:|
  Rat   631 VCQKPGDLVMCNQCEFCFHLDCHLPSLQDVP--GEEWSCSLCHVLPDLKEEDGSLSLDGADSTGV 693

  Fly   962 --ELSALELRILQRICLELYCQYEQSLNFREPESP----ANTSYYEIVSSP-------------- 1006
              :||....|..:|:.|.|:|        .||..|    |..|.:.:||||
  Rat   694 VAKLSPANQRKCERVLLALFC--------HEPCRPLHQLATDSTFSMVSSPRIGEVAGVKLVAPL 750

  Fly  1007 --------------MSLDVIRTRLDPSSPNHYKDIAGFVSDVRLIFSNTYLFYQEDTKTYSNAKY 1057
                          :.|.:||.||.......|.....|..||..:|.. :....||.....:...
  Rat   751 NVCCLSLQEQPGGTLDLTLIRARLQEKLSPPYSSPQEFAQDVGRMFKQ-FNKLTEDKADVQSIIG 814

  Fly  1058 LENFFEEQL 1066
            |:.|||.::
  Rat   815 LQRFFETRM 823

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
bon	NP_001262765.1	zf-RING_5	82..130	CDD:291308	16/62 (26%)
		BBOX	239..275	CDD:237988	22/35 (63%)
		BBC	284..409	CDD:128778	29/124 (23%)
		PHD_TIF1_like	899..943	CDD:277016	16/43 (37%)
		Bromo_tif1_like	963..1072	CDD:99934	32/136 (24%)
Trim28	XP_006228170.1	zf-RING_5	66..124	CDD:291308	18/64 (28%)
		BBOX	150..186	CDD:197662	20/35 (57%)
		BBOX	209..247	CDD:237988	22/37 (59%)
		BBC	254..380	CDD:128778	29/125 (23%)
		PHD_TIF1beta	628..670	CDD:277093	17/92 (18%)
		Bromodomain	697..829	CDD:295360	32/136 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	76	1.000	Domainoid score	I8753
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	326	1.000	Inparanoid score	I2393
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D330513at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm45236
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR25462
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	8	8.030