DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment fray and AT4G10730

DIOPT Version :9

Sequence 1:	NP_001303449.2	Gene:	fray / 44233	FlyBaseID:	FBgn0023083	Length:	707	Species:	Drosophila melanogaster
Sequence 2:	NP_192811.4	Gene:	AT4G10730 / 826667	AraportID:	AT4G10730	Length:	711	Species:	Arabidopsis thaliana

Alignment Length:	473	Identity:	183/473 - (38%)
Similarity:	260/473 - (54%)	Gaps:	58/473 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly   153 SRSMTSIPANLSSNNVAGAATLP----GAAAPPEKYTWPNSKDDYELRDVIGVGATAVVHGAYCI 213
            ||...::.|.|.|......|:..    |.....:|..:..:..||:|.:.:|.||:||||.|..:
plant     3 SRFRLALEAVLGSRRRKKMASTSSGGGGGGDKKKKKGFSVNPKDYKLMEEVGYGASAVVHRAIYL 67

  Fly   214 PRNEKCAIKRINLEKWNTSMDELLKEIQAMSSCFHENVVTYHTSFVVREELWLVLRLLEGGSLLD 278
            |.||..|||.::|::.|:::|::.:|.|.|:...|.||:....||.|...||:|:..:..||.|.
plant    68 PTNEVVAIKSLDLDRCNSNLDDIRREAQTMTLIDHPNVIKSFCSFAVDHHLWVVMPFMAQGSCLH 132

  Fly   279 IIKHKMRTSNCKQGVFDEATIATVLKEVLKGLEYFHSNGQIHRDIKAGNILIGDDGTIQIADFGV 343
            ::|......      |:||.|.::|||.||.|:|.|..|.||||:||||||:.|.|.|::.||||
plant   133 LMKAAYPDG------FEEAAICSMLKETLKALDYLHRQGHIHRDVKAGNILLDDTGEIKLGDFGV 191

  Fly   344 SAWLATGRDLSRQKVRHTFVGTPCWMAPEVMEQDHGYDFKADIWSFGITAIEMATGTAPYHKYPP 408
            ||.|....|  ||:.|:|||||||||||||::...||:.|||||||||||:|:|.|.||:.||||
plant   192 SACLFDNGD--RQRARNTFVGTPCWMAPEVLQPGSGYNSKADIWSFGITALELAHGHAPFSKYPP 254

  Fly   409 MKVLMLTLQNDPPTLDTGADDKDQYKAYGKTFRKMIVECLQKEPSKRPTASELLKHAFFKKAKDR 473
            ||||::|:||.||.||.   |:|  |.:.|:|::::..||.|:.:|||||.:||||:|||..|..
plant   255 MKVLLMTIQNAPPGLDY---DRD--KKFSKSFKELVALCLVKDQTKRPTAEKLLKHSFFKNVKPP 314

  Fly   474 KYLTQTLLQSGPSMETRVHKAAKRQPGASGRLHRTVT-------------GEWVW---------- 515
            :...:.|....|.:.||| ||.:.:..|...|....:             |...|
plant   315 EICVKKLFVDLPPLWTRV-KALQAKDAAQLALKGMASADQDAISQSEYQRGVSAWNFNIEDLKEQ 378

  Fly   516 ------------SSEEEDNGGSATGSGTGDRKHPS-SDSDSEDRPMNRLERADSSDSDREEPSPE 567
                        |.|||::.|....:...||...| |...||:  ||..|:|  ||::..||..|
plant   379 ASLLDDDDILTESREEEESFGEQLHNKVNDRGQVSGSQLLSEN--MNGKEKA--SDTEVVEPICE 439

  Fly   568 ITHSVSSATVTPGAPAAA 585
            ...:::|.|.:...||::
plant   440 EKSTLNSTTSSVEQPASS 457

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
fray	NP_001303449.2	STKc_OSR1_SPAK	191..467	CDD:270787	136/275 (49%)
fray	NP_001303449.2	OSR1_C	613..670	CDD:403428
AT4G10730	NP_192811.4	STKc_OSR1_SPAK	45..308	CDD:270787	136/275 (49%)
AT4G10730	NP_192811.4	S_TKc	47..308	CDD:214567	135/273 (49%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	289	1.000	Domainoid score	I366
eggNOG	1	0.900	-	-		E1_KOG0582
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D855861at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm2448
orthoMCL	1	0.900	-	-		OOG6_101073
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X1048
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	8	7.680