DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment fray and Strada

DIOPT Version :9

Sequence 1:	NP_001303449.2	Gene:	fray / 44233	FlyBaseID:	FBgn0023083	Length:	707	Species:	Drosophila melanogaster
Sequence 2:	NP_001239377.1	Gene:	Strada / 72149	MGIID:	1919399	Length:	431	Species:	Mus musculus

Alignment Length:	384	Identity:	120/384 - (31%)
Similarity:	170/384 - (44%)	Gaps:	76/384 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly   137 GTPPPHTVAPGNGTASSRSMTSI--PANLSSNNVAGAATLPGAAAPPEKYTWPNSKDDYELRDVI 199
            |..||.........|||.|:.|.  |..:||       .||....             |||..:|
Mouse    31 GEQPPGDTRRKANEASSESIASFSKPEMMSS-------FLPEGGC-------------YELLTII 75

  Fly   200 GVG--ATAVVHGAYCIPRNEKCAIKRINLEKWNTSMDELLKEIQAMSSCF-HENVVTYHTSFVVR 261
            |.|  ....|:.|...|..|...::|||||..:..|...|:....:|..| |.|:|.|..:|:..
Mouse    76 GKGFEDLMTVNLARYKPTGEYVTVRRINLEACSNEMVTFLQGELHVSKLFSHPNIVPYRATFIAD 140

  Fly   262 EELWLVLRLLEGGSLLDII-KHKMRTSNCKQGVFDEATIATVLKEVLKGLEYFHSNGQIHRDIKA 325
            .|||:|...:..||..|:| .|.|...|       |..||.:|:.|||.|:|.|..|.:||.:||
Mouse   141 NELWVVTSFMAYGSAKDLIGTHFMDGMN-------ELAIAYILQGVLKALDYIHHMGYVHRSVKA 198

  Fly   326 GNILIGDDGTIQIADFGVSAWLATGRDLSRQKVRHTF----VGTPCWMAPEVMEQD-HGYDFKAD 385
            .:|||..||.:.::  |:.:.|:......||:..|.|    :....|::|||::|: .|||.|:|
Mouse   199 SHILISTDGKVYLS--GLRSNLSMISHGQRQRAVHDFPKYSIKVLPWLSPEVLQQNLQGYDAKSD 261

  Fly   386 IWSFGITAIEMATGTAPYHKYPPMKVLMLTLQNDPP-TLDT-------------------GADDK 430
            |:|.||||.|:|.|..|:...|..::|:..|....| .|||                   |.:|.
Mouse   262 IYSVGITACELANGHVPFKDMPATQMLLEKLNGTVPCLLDTSTIPAEELTMSPSRSIANPGLNDS 326

  Fly   431 ----------------DQYKAYGKTFRKMIVECLQKEPSKRPTASELLKHAFFKKAKDR 473
                            ..::.:...|...:.:|||:.|..||.||.||.|:|||:.|.|
Mouse   327 LAAGSLRPSNGDSPSHPYHRTFSPHFHNFVEQCLQRNPDARPNASTLLNHSFFKQIKRR 385

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
fray	NP_001303449.2	STKc_OSR1_SPAK	191..467	CDD:270787	102/320 (32%)
fray	NP_001303449.2	OSR1_C	613..670	CDD:403428
Strada	NP_001239377.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	32..52		6/19 (32%)
		PK_STRAD_alpha	70..396	CDD:173767	106/325 (33%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	314..344		2/29 (7%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0582
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810