DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment fray and Stradb

DIOPT Version :9

Sequence 1:	NP_001303449.2	Gene:	fray / 44233	FlyBaseID:	FBgn0023083	Length:	707	Species:	Drosophila melanogaster
Sequence 2:	NP_001102777.2	Gene:	Stradb / 501146	RGDID:	1559449	Length:	418	Species:	Rattus norvegicus

Alignment Length:	336	Identity:	103/336 - (30%)
Similarity:	151/336 - (44%)	Gaps:	75/336 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly   193 YELRDVIGVGATAV--VHGAYCIPRNEKCAIKRINLEKWNTSMDELLKEIQ---AMSSCF-HENV 251
            |||...||.|...:  ||.|...|......||..|||   |..||.|:.:|   .:|..| |.|:
  Rat    58 YELHVEIGRGFDNLTSVHLARHTPTGTLVTIKITNLE---TCTDERLRALQRAVILSHFFQHPNI 119

  Fly   252 VTYHTSFVVREELWLVLRLLEGGSLLDIIKHKMRTSNCKQGVFDEATIATVLKEVL----KGLEY 312
            .||.|.|.|...||::...:..||...:    :||      .|.:....|:::.:|    :||.|
  Rat   120 TTYWTVFTVGSWLWVIYPFMAYGSASQL----LRT------YFPDGMSETLIRNILFGAVRGLNY 174

  Fly   313 FHSNGQIHRDIKAGNILIGDDGTIQIADFGVSAWLATGRDLSRQKVRHTFV--------GTPCWM 369
            .|.||.|||..||.:|||..||.:.::.      |:....|.:...||..|        ....|:
  Rat   175 LHQNGCIHRSFKASHILISGDGLVTLSG------LSHLHSLVKHGQRHRAVFDFPQFSTSVQPWL 233

  Fly   370 APEVMEQD-HGYDFKADIWSFGITAIEMATGTAPYH------------KYPPMKVLMLT------ 415
            :||::.|| |||:.|:||:|.||||.|:|:|..|:.            |.||...|.::
  Rat   234 SPELLRQDLHGYNVKSDIYSVGITACELASGQVPFQDMHSTQMLLQKLKGPPYSPLDVSIFPQSD 298

  Fly   416 --LQNDPPTLDTGADDK-----------------DQYKAYGKTFRKMIVECLQKEPSKRPTASEL 461
              ::|....:|:|..:.                 ...:.:...|..::..|||::|.|||:||.|
  Rat   299 SRMRNSQSGVDSGIGESVLVSTGTHTVNSDRLHTPSTRTFSPAFFSLVQLCLQQDPEKRPSASSL 363

  Fly   462 LKHAFFKKAKD 472
            |.|.|||:.|:
  Rat   364 LSHVFFKQMKE 374

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
fray	NP_001303449.2	STKc_OSR1_SPAK	191..467	CDD:270787	99/329 (30%)
fray	NP_001303449.2	OSR1_C	613..670	CDD:403428
Stradb	NP_001102777.2	S_TKc	58..369	CDD:214567	99/329 (30%)
Stradb	NP_001102777.2	PK_STRAD_beta	59..386	CDD:270864	102/335 (30%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0582
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810