Protein Alignment fray and Mekk1

DIOPT Version :10

• Sequence 1: NP_001303449.2
• Gene: fray / 44233
• FlyBaseID: FBgn0023083
• Length: 707
• Species: Drosophila melanogaster
• Sequence 2: NP_732373.1
• Gene: Mekk1 / 42253
• FlyBaseID: FBgn0024329
• Length: 1571
• Species: Drosophila melanogaster
• Alignment Length: 586
• Identity: 139/586 - (23%)
• Similarity: 213/586 - (36%)
• Gaps: 168/586 - (28%)

  Fly    28 ESQERDPKDTG------IFGCFAKKEEQQHNPKKKQSEG----PRESSNSGSYKVQQTEQEQRRE 82
            |.:..|.||:|      ..|..|..:...|...::...|    ||.:|....:.:...:
  Fly  1027 EQKIMDQKDSGAHTVDLALGIIAYAKMWMHFVMERCERGRGMRPRWASQGLEFLILACD------ 1085

  Fly    83 SENEHPSVYRQ-QDEEFHPIKKE-------------EPQKTPPISKQPRPRNTPRSQSQPAINNR 133
                 |.:.:. .|:||..:|::             ||:|.......||.|.|    |.||.:..
  Fly  1086 -----PQITQHLDDDEFEALKQQMDRCISHVIGITSEPEKVAKKKASPRTRKT----SSPATSRS 1141

  Fly   134 RRP-GTP-----------PPHTVAPGN--------------GTA----SSRSMTSIPANLSSNNV 168
            |.| .||           ||....|.|              ||:    .|......|...|:|
  Fly  1142 RTPTRTPMSAGMVLNPNTPPLQSPPYNKLLHPQFSLKEDVSGTSYSPVDSSDYVDTPCQRSAN-- 1204

  Fly   169 AGAATL-----PGAAAPPEKYTWP--------------------------------------NSK 190
             |...|     |...|.|.|.:..                                      ||.
  Fly  1205 -GELRLLVPQTPPTPASPGKSSLESTPLALRQERVRDAVNRLDMDLEDGLRERRLIGQVKSLNSS 1268

  Fly   191 DDYELRD-----------VIGVGATAVVHGAYCIPRNEKCAIKRINLEKWNT-SMDELLKEIQAM 243
            |...:|.           .||.|....|:.|......|..|:|.|.::...| ::..:.:|::.:
  Fly  1269 DKVHIRARSVHFRWHRGIKIGQGRFGKVYTAVNNNTGELMAMKEIAIQPGETRALKNVAEELKIL 1333

  Fly   244 SSCFHENVVTYHTSFVVREELWLVLRLLEGGSLLDIIKHKMRTSNCKQGVFDEATIATVLKEVLK 308
            ....|:|:|.|:...|.||||.:.:.|...|:|..:::        ..|...||.......::|.
  Fly  1334 EGIKHKNLVRYYGIEVHREELLIFMELCSEGTLESLVE--------LTGNLPEALTRRFTAQLLS 1390

  Fly   309 GLEYFHSNGQIHRDIKAGNI-LIGDDGTIQIADFGVSAWLATGRDLSRQKVR-HT--------FV 363
            |:...|.:|.:|||||..|| |:....::::.|||           |..|:: ||        :|
  Fly  1391 GVSELHKHGIVHRDIKTANIFLVDGSNSLKLGDFG-----------SAVKIQAHTTVPGELQGYV 1444

  Fly   364 GTPCWMAPEVMEQDH--GYDFKADIWSFGITAIEMATGTAPYHKYPPMKVLMLTLQNDPPTLDTG 426
            ||..:|||||..:.:  |:...|||||.|...:|||:|..|:.::.....:|..:         |
  Fly  1445 GTQAYMAPEVFTKTNSDGHGRAADIWSVGCVVVEMASGKRPWAQFDSNFQIMFKV---------G 1500

  Fly   427 ADDKDQY-KAYGKTFRKMIVECLQKEPSKRPTASELLKHAFFKKAKDRKYLTQTLLQSGPSMETR 490
            ..:|.|. ::..:.....|..|||.:|.:|.||.|||:|.|.|..:|.....|..:|...|....
  Fly  1501 MGEKPQAPESLSQEGHDFIDHCLQHDPKRRLTAVELLEHNFCKYGRDECSSEQLQMQVRGSFRRN 1565

  Fly   491 V 491
            |
  Fly  1566 V 1566

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
fray	NP_001303449.2	STKc_OSR1_SPAK	191..467	CDD:270787	83/300 (28%)
		OSR1_C	613..670	CDD:463491
Mekk1	NP_732373.1	MEKK4_N	105..>930	CDD:466077
		STKc_MEKK4	1281..1542	CDD:270796	81/288 (28%)