DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment fray and ppk11

DIOPT Version :9

Sequence 1:	NP_001303449.2	Gene:	fray / 44233	FlyBaseID:	FBgn0023083	Length:	707	Species:	Drosophila melanogaster
Sequence 2:	NP_594517.1	Gene:	ppk11 / 2541473	PomBaseID:	SPAC2C4.14c	Length:	312	Species:	Schizosaccharomyces pombe

Alignment Length:	326	Identity:	117/326 - (35%)
Similarity:	169/326 - (51%)	Gaps:	23/326 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly   190 KDDYELRDVIGVGATAVVHGAYCIPRNEKCAIKRINLEKWNTSMDELLKEIQAMSSCFHENVVTY 254
            |..|....:||.|:...|..|..:..::..|:|.::|:.....::.|.:||..:......::..|
pombe     3 KHQYRDLQLIGQGSFGSVFRAQDVESSKIVALKVVDLDATKDQIETLTQEINFLIDLNSVHITKY 67

  Fly   255 HTSFVVREELWLVLRLLEGGSLLDIIKHKMRTSNCKQGVFDEATIATVLKEVLKGLEYFHSNGQI 319
            :.|||....||:.:...:|||.||::|        ..|.|.|..||.|:::||:.|.|.|..|::
pombe    68 YASFVDGFRLWITMEYCDGGSCLDLLK--------LSGTFSERVIAEVMRQVLEALVYLHGQGKM 124

  Fly   320 HRDIKAGNILIGDDGTIQIADFGVSAWLATGRDLSRQKVRHTFVGTPCWMAPEVMEQDHGYDFKA 384
            ||||||.|||...||.:::||||||..|.:.||.:     ..|||||.||||||::|. ||::||
pombe   125 HRDIKAANILTMKDGLVKLADFGVSGQLESLRDKN-----DDFVGTPFWMAPEVVKQT-GYNYKA 183

  Fly   385 DIWSFGITAIEMATGTAPYHKYPPMKVLMLTLQNDPPTLDTGADDKDQYKAYGKTFRKMIVECLQ 449
            ||||.||||.|:|||..||....|||||:|..::.||:|:.        ..:.:.|...:..||:
pombe   184 DIWSLGITAYELATGEPPYSGIHPMKVLLLIPKHSPPSLER--------SKFSRAFCDFVSNCLK 240

  Fly   450 KEPSKRPTASELLKHAFFKKAKDRKYLTQTLLQSGPSMETRVHKAAKRQPGASGRLHRTVTGEWV 514
            |.|..|.||..|.||.|.||......:.:.:.......|:.:...|.......|....|: .|.|
pombe   241 KNPKDRATAEYLSKHKFIKKYCPNTSVKEVVASYAKWKESELLPEATPYNSTMGNSANTI-DEVV 304

  Fly   515 W 515
            |
pombe   305 W 305

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
fray	NP_001303449.2	STKc_OSR1_SPAK	191..467	CDD:270787	106/275 (39%)
fray	NP_001303449.2	OSR1_C	613..670	CDD:403428
ppk11	NP_594517.1	STKc_MST3_like	4..278	CDD:270786	109/295 (37%)
ppk11	NP_594517.1	S_TKc	6..258	CDD:214567	106/273 (39%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910