DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ND-PDSW and NDUFB10

DIOPT Version :9

Sequence 1:	NP_651972.1	Gene:	ND-PDSW / 44228	FlyBaseID:	FBgn0021967	Length:	159	Species:	Drosophila melanogaster
Sequence 2:	NP_004539.1	Gene:	NDUFB10 / 4716	HGNCID:	7696	Length:	172	Species:	Homo sapiens

Alignment Length:	167	Identity:	53/167 - (31%)
Similarity:	92/167 - (55%)	Gaps:	18/167 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 PEP-------RSPMASFAESVLNVIDGPITWFRESIVEPNQQKQN---WYHQRFRRVPTIDQCYT 56
            |||       .:|:....::...::|.|:|..||.|  ..|..:|   :||:::||||.|.:|..
Human    11 PEPPRRTPVQPNPIVYMMKAFDLIVDRPVTLVREFI--ERQHAKNRYYYYHRQYRRVPDITECKE 73

  Fly    57 DDAVCRFEADQQFRRDRMVDNEIVNILRQRFEDCTLYEAPDHMVKCRPLMDQYEKATENWFIKYG 121
            :|.:|.:||:.|::||..||.||:||::.|.:.|...|..::...|...::|:.:..:.:..:|.
Human    74 EDIMCMYEAEMQWKRDYKVDQEIINIMQDRLKACQQREGQNYQQNCIKEVEQFTQVAKAYQDRYQ 138

  Fly   122 DLGGYANAKTAYMKQKHRLIWERRHGPVGSGMKEEAA 158
            |||.|::|:....||:.|::.||:      ..||.||
Human   139 DLGAYSSARKCLAKQRQRMLQERK------AAKEAAA 169

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ND-PDSW	NP_651972.1	NDUFB10	20..145	CDD:402040	44/127 (35%)
NDUFB10	NP_004539.1	NDUFB10	36..161	CDD:287251	43/126 (34%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165159726
Domainoid	1	1.000	95	1.000	Domainoid score	I7451
eggNOG	1	0.900	-	-		E1_KOG4009
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H3343
Inparanoid	1	1.050	98	1.000	Inparanoid score	I5033
Isobase	1	0.950	-	0	Normalized mean entropy	S5236
OMA	1	1.010	-	-		QHG45745
OrthoDB	1	1.010	-	-		D1364322at2759
OrthoFinder	1	1.000	-	-		FOG0007421
OrthoInspector	1	1.000	-	-		oto88650
orthoMCL	1	0.900	-	-		OOG6_108080
Panther	1	1.100	-	-	LDO	PTHR13094
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R4136
SonicParanoid	1	1.000	-	-		X5553
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	17	16.750