DRSC/TRiP Functional Genomics Resources

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Protein Alignment Sr-CII and Mamdc2

DIOPT Version :10

Sequence 1:NP_524720.2 Gene:Sr-CII / 44219 FlyBaseID:FBgn0020377 Length:599 Species:Drosophila melanogaster
Sequence 2:XP_036017587.1 Gene:Mamdc2 / 71738 MGIID:1918988 Length:689 Species:Mus musculus


Alignment Length:217 Identity:67/217 - (30%)
Similarity:92/217 - (42%) Gaps:45/217 - (20%)


- Green bases have known domain annotations that are detailed below.


  Fly   121 QLGACRRSNH--TMDHSCDFESEDQCGWSAEETIWLPWKRISAVTDFHHPRTGPRYDHTFGNTSG 183
            |||.||....  .....|.|: :|:|.::.|:.....|.|....|...:  |||:.|||   |..
Mouse   495 QLGNCRSPARLPPPPGECTFD-QDECAFTQEKRNRSSWHRGRGETPTSY--TGPKGDHT---TGV 553

  Fly   184 GHYMRMETQIEAYG-SYHFVS-PV--YPRSLCLNVACCFRFHYFMFGAGVDRLVLSVKPASLQID 244
            |:||.:|.....|| ..|.:| |:  .|...||.      |.|.|:|||...|.:.:|       
Mouse   554 GYYMYIEASHMVYGQKAHLLSQPLRGVPGKHCLT------FFYHMYGAGTGLLSVYLK------- 605

  Fly   245 DMWNSFRSNSSKFEI----TGSQGTHWLENTI--TIDKMHEDFQVVFTATDARSQFGDIAIDDVK 303
                  |...|:..:    .|.|...||...:  :..:.|   |::|.||...|...||||||||
Mouse   606 ------REEDSEESLLWRRRGEQSISWLRALVEYSCRRRH---QIIFEATRGVSIRSDIAIDDVK 661

  Fly   304 LMTGSECGVDGYSTTTTTESAS 325
            |..|...|::     .|||.:|
Mouse   662 LQAGPCAGME-----DTTEQSS 678

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Sr-CIINP_524720.2 PHA02927 <22..127 CDD:222943 4/5 (80%)
Sushi 27..72 CDD:459664
MAM 136..311 CDD:459878 57/184 (31%)
Somatomedin_B 340..388 CDD:460034
Mamdc2XP_036017587.1 MAM 26..170 CDD:99706
MAM 173..330 CDD:459878
MAM 345..500 CDD:459878 3/4 (75%)
MAM 512..667 CDD:99706 57/182 (31%)
Blue background indicates that the domain is not in the aligned region.

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