Protein Alignment Sr-CII and Mamdc4

DIOPT Version :10

• Sequence 1: NP_524720.2
• Gene: Sr-CII / 44219
• FlyBaseID: FBgn0020377
• Length: 599
• Species: Drosophila melanogaster
• Sequence 2: NP_001074668.2
• Gene: Mamdc4 / 381352
• MGIID: 2685841
• Length: 1232
• Species: Mus musculus
• Alignment Length: 212
• Identity: 67/212 - (31%)
• Similarity: 87/212 - (41%)
• Gaps: 56/212 - (26%)

  Fly   119 STQLGACRRSNHTMDHSCDFESEDQCGWSAEETIWLPWKRI--------SAVTDFHHPRTGPRYD 175
            |.|.|.|.:..     |||||: ..||||     .|||..:        |..|...:|:  |..|
Mouse   971 SLQDGPCPQPG-----SCDFET-GLCGWS-----HLPWPSLGGYSWDWSSGATPSRYPQ--PSVD 1022

  Fly   176 HTFGNTSGGHYMRMETQIEAYGSYHFVSPVYPRS--LCLNVACCFRFHYFM-----FGAGVDRLV 233
            ||.| |..||:...||.:...|.    ...:.||  |......|.||.|:|     |..|..|::
Mouse  1023 HTLG-TEAGHFAFFETSVLGPGG----QAAWLRSEPLPATTVSCLRFWYYMGFPEHFYKGELRVL 1082

  Fly   234 LSVKPASLQIDDMWNSFRSNSSKFEITGSQGTH----WLENTITIDKMHEDFQVVFTAT-DARSQ 293
            ||.....|.:   |              .||.|    ||:..|.:.. .|:||:||.|| ..:..
Mouse  1083 LSSARGQLAV---W--------------YQGGHLRDQWLQVQIELSN-SEEFQIVFEATLGGQPA 1129

  Fly   294 FGDIAIDDVKLMTGSEC 310
            .|.||||||:.:.|.:|
Mouse  1130 LGPIAIDDVQYLAGQQC 1146

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sr-CII	NP_524720.2	PHA02927	<22..127	CDD:222943	4/7 (57%)
		Sushi	27..72	CDD:459664
		MAM	136..311	CDD:459878	62/195 (32%)
		Somatomedin_B	340..388	CDD:460034
Mamdc4	NP_001074668.2	MAM	66..224	CDD:214533
		LDLa	234..266	CDD:238060
		MAM	254..427	CDD:214533
		LDLa	462..495	CDD:238060
		MAM	498..652	CDD:459878
		MAM	660..817	CDD:214533
		MAM	823..978	CDD:459878	3/6 (50%)
		MAM	978..1144	CDD:214533	61/201 (30%)