Protein Alignment Sr-CII and Sr-CI

DIOPT Version :10

• Sequence 1: NP_524720.2
• Gene: Sr-CII / 44219
• FlyBaseID: FBgn0020377
• Length: 599
• Species: Drosophila melanogaster
• Sequence 2: NP_477102.1
• Gene: Sr-CI / 33621
• FlyBaseID: FBgn0014033
• Length: 629
• Species: Drosophila melanogaster
• Alignment Length: 639
• Identity: 337/639 - (52%)
• Similarity: 435/639 - (68%)
• Gaps: 50/639 - (7%)

  Fly     1 MQFFLALTLILAYSLDTANGSCEGSLDLENGRFFTRSNNLVIFQCNRGFVLQGNSIHTCDRDGRL 65
            |:||..|.:|:.|.:...:|.||.|:||:||....|..|:|.|:||||:.|||..:.||||||||
  Fly     1 MEFFWTLAVIVIYCIGHIHGRCERSIDLDNGSINYRQRNVVRFRCNRGYTLQGTVMQTCDRDGRL 65

  Fly    66 REKKPFCARKGCDKPEDPTNGYVLDNPVKAEIVCLDGFVLYGSRTAFCDGEKWSTQLGACRRSNH 130
            |.:|||||.:||.:||||.||:|.:..::|::||.||:||.|.|||:||||:||||||:||||||
  Fly    66 RGEKPFCASRGCARPEDPENGHVENLSLRADVVCHDGYVLVGGRTAYCDGERWSTQLGSCRRSNH 130

  Fly   131 TMDHSCDFESEDQCGWSAEETIWLPWKRISAVTDFHHPRTGPRYDHTFGNTSGGHYMRMETQIEA 195
            |.||||||||||||||.||.|...||||:|.|:|.|..|||||:||||.|.|||||||||||:.|
  Fly   131 TRDHSCDFESEDQCGWEAETTFRRPWKRVSTVSDIHSLRTGPRHDHTFKNESGGHYMRMETQMGA 195

  Fly   196 YGSYHFVSPVYPRSLCLNVACCFRFHYFMFGAGVDRLVLSVKPASLQIDDMWNSFRSNSSKFEIT 260
            |||||.:||:|||||.|..||||||||||||||||.||:||||.|:.:..|||.||:|.|||||:
  Fly   196 YGSYHLLSPIYPRSLTLKTACCFRFHYFMFGAGVDNLVVSVKPVSMPMATMWNRFRANCSKFEIS 260

  Fly   261 GSQGTHWLENTITIDKMHEDFQVVFTATDARSQFGDIAIDDVKLMTGSECGVDGYSTTTTTESAS 325
            |.|||.|||:||:||:|.|||||:|||||||||||||||||||||||||||.:|:||||   ..:
  Fly   261 GQQGTQWLEHTISIDEMQEDFQVIFTATDARSQFGDIAIDDVKLMTGSECGTNGFSTTT---EPT 322

  Fly   326 SAMSSSEEPLVFDMMSCTFRCG-SISPGSPLFSDEGIVMSCGCDDSCILNNNCCPNYFEKCVKEL 389
            :...|:|:|||:|||||:.||| |||..:  .::.||||.|||:|.|:.:..||.||.|:|.|||
  Fly   323 APTGSNEQPLVYDMMSCSGRCGTSISASN--ITNNGIVMGCGCNDECLSDETCCLNYLEECTKEL 385

  Fly   390 ------DIGS-NVFLNSANTTTTSISRNTTTEKVFSISLEASRSFTTPRTSTNSTTFPRTQISTK 447
                  ||.| ...:.|.:|:||..|..|||....:.|...::..||..|:|.:||..|| .:||
  Fly   386 LTTTEDDISSLPPTVTSTSTSTTRKSTTTTTTSTTTTSTTTTKRPTTTTTTTKATTTKRT-TTTK 449

  Fly   448 KLLNTHET---LTETSTIP-----TRNKKLSQP------SIFSSQHITV--------------TT 484
            |...|..|   .|.|||.|     |.:...:.|      ::|:::..|:              ||
  Fly   450 KPTTTSTTPKPTTTTSTTPKSTTSTTSTTSTTPTTTTTINVFTTKKTTIMIPTSSTEKTTGINTT 514

  Fly   485 TTDRSRKDYH---EDIAGQLDMNTNIPHPALIVMYLLIGVILVIVVANLKQLCKILSKNSSRDNE 546
            ...|.|..::   :||.|.:|.:.:.|:|||:|:|||:.::||:|:||:.....|....|...:|
  Fly   515 MKTRKRITWNVDPQDIEGHMDTSGSTPNPALVVLYLLLAIVLVVVLANVVNRWIIPITGSKTSSE 579

  Fly   547 KVVSFKKAFEGLRKPRRLSQNCNGM-DQHLCSAFDEDLDYFEDMDMNIRMVTDL 599
            |.|.|||||:.|:|.|:.    |.| ||.||.:.::|::|||:|.::||..|||
  Fly   580 KAVRFKKAFDSLKKQRKR----NSMDDQPLCDSDNDDVEYFEEMGVDIRHRTDL 629

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sr-CII	NP_524720.2	PHA02927	<22..127	CDD:222943	63/104 (61%)
		Sushi	27..72	CDD:459664	26/44 (59%)
		MAM	136..311	CDD:459878	133/174 (76%)
		Somatomedin_B	340..388	CDD:460034	24/48 (50%)
Sr-CI	NP_477102.1	CCP	22..72	CDD:214478	29/49 (59%)
		CCP	77..125	CDD:214478	29/47 (62%)
		MAM	131..308	CDD:214533	134/176 (76%)
		Somatomedin_B	335..385	CDD:470596	27/51 (53%)