DRSC/TRiP Functional Genomics Resources

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Protein Alignment Sr-CII and Mamdc2

DIOPT Version :10

Sequence 1:NP_524720.2 Gene:Sr-CII / 44219 FlyBaseID:FBgn0020377 Length:599 Species:Drosophila melanogaster
Sequence 2:NP_001094166.1 Gene:Mamdc2 / 309410 RGDID:1305129 Length:686 Species:Rattus norvegicus


Alignment Length:197 Identity:60/197 - (30%)
Similarity:80/197 - (40%) Gaps:36/197 - (18%)


- Green bases have known domain annotations that are detailed below.


  Fly   121 QLGACRRSNH--TMDHSCDFESEDQCGWSAEETIWLPWKRISAVTDFHHPRTGPRYDHTFGNTSG 183
            |||.||....  .....|.|: :|:|.::.|:.....|.|....|...:  |||:.|||   |..
  Rat   492 QLGNCRSPERLPPPPGECTFD-QDECAFTQEKRNRSSWHRGRGETPTSY--TGPKGDHT---TGV 550

  Fly   184 GHYMRMETQIEAYG-SYHFVS-PV--YPRSLCLNVACCFRFHYFMFGAGVDRLVLSVKPASLQID 244
            |:||.:|.....|| ..|.:| |:  .|...||      .|.|.|:|||...|.:.:|       
  Rat   551 GYYMYIEASHMVYGQKAHLLSQPLRGVPGKHCL------IFFYHMYGAGTGLLSVYLK------- 602

  Fly   245 DMWNSFRSNSSKFEI----TGSQGTHWLENTITIDKMHEDFQVVFTATDARSQFGDIAIDDVKLM 305
                  |...||..:    .|.|...||...:......: .|::|.|....|...||||||||..
  Rat   603 ------REEDSKESLLWRRKGEQSISWLRALVEYSSRRQ-HQIIFEAIRGVSIRSDIAIDDVKFQ 660

  Fly   306 TG 307
            .|
  Rat   661 AG 662

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Sr-CIINP_524720.2 PHA02927 <22..127 CDD:222943 4/5 (80%)
Sushi 27..72 CDD:459664
MAM 136..311 CDD:459878 55/180 (31%)
Somatomedin_B 340..388 CDD:460034
Mamdc2NP_001094166.1 MAM 26..167 CDD:99706
MAM 170..327 CDD:459878
MAM 342..497 CDD:459878 3/4 (75%)
MAM 509..664 CDD:99706 55/180 (31%)
Blue background indicates that the domain is not in the aligned region.

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