DRSC/TRiP Functional Genomics Resources

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Protein Alignment Sr-CII and si:dkey-163f14.6

DIOPT Version :10

Sequence 1:NP_524720.2 Gene:Sr-CII / 44219 FlyBaseID:FBgn0020377 Length:599 Species:Drosophila melanogaster
Sequence 2:XP_009304399.1 Gene:si:dkey-163f14.6 / 100332398 ZFINID:ZDB-GENE-141215-18 Length:740 Species:Danio rerio


Alignment Length:541 Identity:113/541 - (20%)
Similarity:184/541 - (34%) Gaps:157/541 - (29%)


- Green bases have known domain annotations that are detailed below.


  Fly     8 TLILAY-------SLDTANGSCEGSLDLENGRFFTRSNNL-VIFQCNRGFVLQGNSIHTCDRDGR 64
            ||:.|:       :..:|:..|.|...|||||.|.|...| |.|.||.||.:.|....:| ..|:
Zfish     7 TLLCAFLSPLWTLTPGSADKGCSGFGHLENGRMFFRYGGLYVTFTCNPGFRIHGYRTSSC-VSGQ 70

  Fly    65 LREKKPFCARKGCDKPEDPTNGYVL---DNPVKAEIVCLDGFVLYGSRTAFCDGEKWSTQLGACR 126
            .....|.|...||..|.|..:|..:   |..: |...|..||.|.||...:|.|:.|::....|:
Zfish    71 WARDPPLCVASGCPGPGDLLHGSAVVSRDRSL-ASFSCDAGFYLSGSALLYCKGKNWNSTKPVCK 134

  Fly   127 RSNHTMDHSCDFESEDQCGWSAEETIWLPWKRISAV----TDFHHPRTGPRYDHTFGNTSGGHYM 187
            .::                             |.:|    .:|.|   ||.|             
Zfish   135 VAD-----------------------------IMSVLHLNQEFLH---GPAY------------- 154

  Fly   188 RMETQIEAYGSYHFVSPVYPRSLCLN-VACCFRFHYFMFGAGVDRLVLSVKPASLQIDDMWNSFR 251
             :.|.::.:...|           || :|.......|:..|     :|.|...:|.:.|...:.|
Zfish   155 -VPTSLKNHLHSH-----------LNTMAITAHKDTFLKSA-----LLEVPHVTLDLTDDKQTSR 202

  Fly   252 -------SNSSKFEITGSQGTHWLENTITIDKMHEDFQV---VFTATDARSQFGDIAIDDVKLMT 306
                   |.|..|.....:....:::.|....:.:...|   |.|.:.|.|.:            
Zfish   203 KPVEKKPSKSVLFAAEPIKNPENIKDLIRSSDLQKPVPVTSNVNTMSFASSFY------------ 255

  Fly   307 GSECGVDGYSTTTTTESASSAMSSSEEPLVFDMMSCTFRCGSISPGSPLFSDEGIVMSCGCDDSC 371
                   .:..|||:.|.::...:|::..:.|.|...         :|...:|.     |...:|
Zfish   256 -------NFILTTTSSSFNTPSVNSQQVKIMDQMFTE---------TPYRRNEK-----GYQSTC 299

  Fly   372 ILNNNCCPNYFEKCVKELDIGSNVFLNSANTTTTSISRNT--TTEKVFS--ISLEASRSFTTPRT 432
            :.:........|:.::        :|.:...||.:.:.||  |.:.:.|  :..|.|.:|.:|..
Zfish   300 VTDTTSVTTSAERLLE--------YLKNKPLTTLAPNINTLGTNDYLQSGILDNEHSATFKSPTA 356

  Fly   433 STNSTTFPRTQISTKKLLN--------THETLTE---TSTIPTRNKKLSQPSIFSSQHITVT-TT 485
            |     :||..:|..:..|        |...|.|   ..|.|:.|     |...:|..:.:| ..
Zfish   357 S-----YPRFMLSENESANYLKPTAPSTCRGLCEQDVQKTSPSTN-----PIGHASSSMQITKIA 411

  Fly   486 TDRSRKDYHEDIAGQLDMNTN 506
            :|....|.|..|....|...|
Zfish   412 SDLPPVDVHRFIYNAEDQQVN 432

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Sr-CIINP_524720.2 PHA02927 <22..127 CDD:222943 38/108 (35%)
Sushi 27..72 CDD:459664 18/45 (40%)
MAM 136..311 CDD:459878 28/189 (15%)
Somatomedin_B 340..388 CDD:460034 6/47 (13%)
si:dkey-163f14.6XP_009304399.1 PHA02927 <17..>135 CDD:222943 39/119 (33%)
CCP 461..521 CDD:214478
FXa_inhibition 527..563 CDD:464251
EGF_CA 565..604 CDD:214542
EGF_CA 606..647 CDD:214542
EGF_CA 648..689 CDD:214542
FXa_inhibition 694..724 CDD:464251
Blue background indicates that the domain is not in the aligned region.

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