DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ND-23 and ndufs8a

DIOPT Version :9

Sequence 1:	NP_524719.1	Gene:	ND-23 / 44207	FlyBaseID:	FBgn0017567	Length:	217	Species:	Drosophila melanogaster
Sequence 2:	NP_998304.1	Gene:	ndufs8a / 406413	ZFINID:	ZDB-GENE-040426-2153	Length:	210	Species:	Danio rerio

Alignment Length:	220	Identity:	159/220 - (72%)
Similarity:	179/220 - (81%)	Gaps:	13/220 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MSLTMR-IFTASRNGQRLFGSHGAR--LLAAQRAEPKDIVEVPKGYVYVNNKELSMEFADITDRA 62
            ||..:| ::||||.|..|...:..|  .|:|.||          |..||||:|.:.::..|||||
Zfish     1 MSAALRVVYTASRPGSFLACQNLIRPFSLSAHRA----------GIKYVNNQEEATDWKSITDRA 55

  Fly    63 ASTMFFGELLRGFAVTLAHIFKEPATINYPFEKGPLSPRFRGEHALRRYPSGEERCIACKLCEAI 127
            |.|:...||:||..:.::::|:|||||||||||||||||||||||||||||||||||||||||||
Zfish    56 AQTLLLTELIRGMGMAVSYLFREPATINYPFEKGPLSPRFRGEHALRRYPSGEERCIACKLCEAI 120

  Fly   128 CPAQAITIEAEERADGSRRTTRYDIDMTKCIYCGFCQEACPVDAIVEGPNFEFSTETHEELLYNK 192
            |||||||||||.|||||||||||||||||||||||||||||||||||||||||||||||||||||
Zfish   121 CPAQAITIEAEPRADGSRRTTRYDIDMTKCIYCGFCQEACPVDAIVEGPNFEFSTETHEELLYNK 185

  Fly   193 EKLLCNGDKWESEIASNLQADHLYR 217
            ||||.||||||:|||:|:|||.|||
Zfish   186 EKLLNNGDKWEAEIAANIQADFLYR 210

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ND-23	NP_524719.1	PRK05888	61..217	CDD:235637	134/155 (86%)
ndufs8a	NP_998304.1	PRK05888	54..210	CDD:235637	134/155 (86%)
ndufs8a	NP_998304.1	Fer4_9	111..161	CDD:289930	48/49 (98%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170581797
Domainoid	1	1.000	120	1.000	Domainoid score	I5728
eggNOG	1	0.900	-	-		E1_COG1143
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H1867
Inparanoid	1	1.050	315	1.000	Inparanoid score	I2536
OMA	1	1.010	-	-		QHG55295
OrthoDB	1	1.010	-	-		D1283957at2759
OrthoFinder	1	1.000	-	-		FOG0004083
OrthoInspector	1	1.000	-	-		otm26329
orthoMCL	1	0.900	-	-		OOG6_100887
Panther	1	1.100	-	-	LDO	PTHR10849
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2670
SonicParanoid	1	1.000	-	-		X2833
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	17	16.800