DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ND-23 and Ndufs8

DIOPT Version :9

Sequence 1:	NP_524719.1	Gene:	ND-23 / 44207	FlyBaseID:	FBgn0017567	Length:	217	Species:	Drosophila melanogaster
Sequence 2:	NP_001258372.1	Gene:	Ndufs8 / 225887	MGIID:	2385079	Length:	212	Species:	Mus musculus

Alignment Length:	218	Identity:	153/218 - (70%)
Similarity:	169/218 - (77%)	Gaps:	19/218 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 SLTMRIFTASRNGQRLFGSHGARLLAAQRAEPKDIVEVPKGYVYVNNKELSME--FADITDRAAS 64
            :|...:.|...|||.|   |.:.:.|.              |.|||.||...|  ....||.||.
Mouse    12 ALAQAMRTGHLNGQSL---HSSAVAAT--------------YKYVNKKEQESEVDMKSATDNAAR 59

  Fly    65 TMFFGELLRGFAVTLAHIFKEPATINYPFEKGPLSPRFRGEHALRRYPSGEERCIACKLCEAICP 129
            .:.:.||:||..:||:::|:|||||||||||||||||||||||||||||||||||||||||||||
Mouse    60 ILMWTELIRGLGMTLSYLFREPATINYPFEKGPLSPRFRGEHALRRYPSGEERCIACKLCEAICP 124

  Fly   130 AQAITIEAEERADGSRRTTRYDIDMTKCIYCGFCQEACPVDAIVEGPNFEFSTETHEELLYNKEK 194
            |||||||||.|||||||||||||||||||||||||||||||||||||||||||||||||||||||
Mouse   125 AQAITIEAEPRADGSRRTTRYDIDMTKCIYCGFCQEACPVDAIVEGPNFEFSTETHEELLYNKEK 189

  Fly   195 LLCNGDKWESEIASNLQADHLYR 217
            ||.||||||:|||:|:|||:|||
Mouse   190 LLNNGDKWEAEIAANIQADYLYR 212

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ND-23	NP_524719.1	PRK05888	61..217	CDD:235637	134/155 (86%)
Ndufs8	NP_001258372.1	PRK05888	56..212	CDD:235637	134/155 (86%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167837997
Domainoid	1	1.000	120	1.000	Domainoid score	I5757
eggNOG	1	0.900	-	-		E1_COG1143
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H1867
Inparanoid	1	1.050	305	1.000	Inparanoid score	I2621
Isobase	1	0.950	-	0	Normalized mean entropy	S2075
OMA	1	1.010	-	-		QHG55295
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0004083
OrthoInspector	1	1.000	-	-		oto93652
orthoMCL	1	0.900	-	-		OOG6_100887
Panther	1	1.100	-	-	LDO	PTHR10849
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2670
SonicParanoid	1	1.000	-	-		X2833
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	17	16.740