DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment spen and RS31a

DIOPT Version :9

Sequence 1:	NP_722615.1	Gene:	spen / 44205	FlyBaseID:	FBgn0016977	Length:	5560	Species:	Drosophila melanogaster
Sequence 2:	NP_182184.1	Gene:	RS31a / 819273	AraportID:	AT2G46610	Length:	250	Species:	Arabidopsis thaliana

Alignment Length:	256	Identity:	59/256 - (23%)
Similarity:	103/256 - (40%)	Gaps:	50/256 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly   656 RTLFIGNLEKDITAGELRSHFEAFGEIIEIDIKKQGLNAYAFCQYSDIVSVVKAMRKMDGEHLGS 720
            |.:::||.:.|....:|...|..||.:..:|:|    :.|||..:.|......|:|:.|....|.
plant     2 RHVYVGNFDYDTRHSDLERLFSKFGRVKRVDMK----SGYAFVYFEDERDAEDAIRRTDNTTFGY 62

  Fly   721 NRIKLGF---------------GKSM----PTNCVWIDGVDE-KVSESFLQSQFTRFGAVTKVSI 765
            .|.||..               ||::    ||..:::...|. :..|..::..|..:|.|..|.:
plant    63 GRRKLSVEWAKDFQGERGKPRDGKAVSNQRPTKTLFVINFDPIRTRERDMERHFEPYGKVLNVRM 127

  Fly   766 DRNRQLALVLYDQVQNAQAAVKDMRGTILRRKKLQVDFASRECQDAFYDKQEKQQQQSSGS---- 826
            .||  .|.|.:...::|..|:.....:.|..|.:.|::|.||..:. .|:....:::.|.|
plant   128 RRN--FAFVQFATQEDATKALDSTHNSKLLDKVVSVEYALREAGER-EDRYAGSRRRRSPSPVYR 189

  Fly   827 -----------NPRFSRYESSASSLQSRS-----RASSFSRHQNNS---NDDCSPINTPGG 868
                       :|.:.||:..|...:.:|     |:|.:.|.:..|   :...|||....|
plant   190 RRPSPDYTRRRSPEYDRYKGPAPYERRKSPDYGRRSSDYGRARARSPGYDRSRSPIQRARG 250

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
spen	NP_722615.1	RRM2_SHARP	555..628	CDD:240795
		RRM3_SHARP	654..726	CDD:240796	20/69 (29%)
		RRM4_SHARP	727..803	CDD:240797	19/95 (20%)
		RILP-like	1997..>2055	CDD:304877
		SPOC	5404..5527	CDD:285043
RS31a	NP_182184.1	RRM_SF	2..73	CDD:302621	21/74 (28%)
RS31a	NP_182184.1	RRM_SF	96..165	CDD:302621	15/70 (21%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910