DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment ScpX and STOML1

DIOPT Version :9

Sequence 1:	NP_524715.2	Gene:	ScpX / 44183	FlyBaseID:	FBgn0015808	Length:	544	Species:	Drosophila melanogaster
Sequence 2:	NP_004800.2	Gene:	STOML1 / 9399	HGNCID:	14560	Length:	398	Species:	Homo sapiens

Alignment Length:	180	Identity:	48/180 - (26%)
Similarity:	80/180 - (44%)	Gaps:	37/180 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly   374 PNAQLALQHNLGLGGAVVVALYRLGFPAANSVVRNLTAAGKAATSEDGFKVAP------------ 426
            ||....||.         :||:.|| .:.||:.....:.|.|.|.|...:|.|
Human   233 PNLDSTLQQ---------LALHFLG-GSMNSMAGGAPSPGPADTVEMVSEVEPPAPQVGARSSPK 287

  Fly   427 ------LLKLLEQAMQEDKDNLIEKVRAIYGFKVNNGPNGQTGFWVIDAKQGKGKI---IFNGTQ 482
                  ||..|:..:.|   .|:.:|.|.|.|.|.. |:|....:.:|...|:|::   :.:|..
Human   288 QPLAEGLLTALQPFLSE---ALVSQVGACYQFNVVL-PSGTQSAYFLDLTTGRGRVGHGVPDGIP 348

  Fly   483 KCDVTFIISDDDVFELLTGKLPPQKAFFQGKIKIQGNMGFAMKLMDLQRS 532
              ||...:::.|:..||..:|.|..|:..|::|::|::..||||..:.|:
Human   349 --DVVVEMAEADLRALLCRELRPLGAYMSGRLKVKGDLAMAMKLEAVLRA 396

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ScpX	NP_524715.2	PRK08256	5..396	CDD:181327	6/21 (29%)
		SCP-x_thiolase	9..395	CDD:238425	5/20 (25%)
		SCP2	429..529	CDD:280250	29/102 (28%)
STOML1	NP_004800.2	Tyrosine-type lysosomal sorting signal. /evidence=ECO:0000255, ECO:0000269\|PubMed:19696025	6..10
		PHB	77..217	CDD:214581
		SPFH_SLP-1	94..224	CDD:259814
		SCP2	304..395	CDD:280250	28/96 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4170
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810