DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment hoip and GADD45A

DIOPT Version :9

Sequence 1:NP_001260293.1 Gene:hoip / 44173 FlyBaseID:FBgn0286786 Length:127 Species:Drosophila melanogaster
Sequence 2:NP_001915.1 Gene:GADD45A / 1647 HGNCID:4095 Length:165 Species:Homo sapiens


Alignment Length:116 Identity:32/116 - (27%)
Similarity:49/116 - (42%) Gaps:22/116 - (18%)


- Green bases have known domain annotations that are detailed below.


  Fly    24 LLQQALNYNQLRKGANEATKTLNRGLADIV--VLAGDAE---PIEILLHLPLL----CE-DKNVP 78
            :|.:||:...:..|..||.|.||....::|  :||.|.:   .:.:.:|..|:    || |.|:.
Human    26 VLSKALSQRTITVGVYEAAKLLNVDPDNVVLCLLAADEDDDRDVALQIHFTLIQAFCCENDINIL 90

  Fly    79 YVFVRSKQA--------LGRAC--GVSR-PIVACSVTTN-EGSQLKSQITS 117
            .|....:.|        .|.|.  |..: |.:.|.:.|| ..||.|....|
Human    91 RVSNPGRLAELLLLETDAGPAASEGAEQPPDLHCVLVTNPHSSQWKDPALS 141

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
hoipNP_001260293.1 SNU13 6..127 CDD:411046 32/116 (28%)
GADD45ANP_001915.1 Ribosomal_L7Ae 21..123 CDD:396000 25/96 (26%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.910

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