Protein Alignment RabX1 and RAB7A

DIOPT Version :10

• Sequence 1: NP_524713.1
• Gene: RabX1 / 44172
• FlyBaseID: FBgn0015372
• Length: 261
• Species: Drosophila melanogaster
• Sequence 2: NP_004628.4
• Gene: RAB7A / 7879
• HGNCID: 9788
• Length: 207
• Species: Homo sapiens
• Alignment Length: 173
• Identity: 59/173 - (34%)
• Similarity: 99/173 - (57%)
• Gaps: 8/173 - (4%)

  Fly     7 KVLVLGSRGVGKTRLVIRYIKNTLHRKESEVPTIAVSFFTCNIILDEVKIKLQIWDTAGQERYRA 71
            ||::||..|||||.|:.:|:......:..  .||...|.|..:::|:..:.:||||||||||:::
Human    10 KVIILGDSGVGKTSLMNQYVNKKFSNQYK--ATIGADFLTKEVMVDDRLVTMQIWDTAGQERFQS 72

  Fly    72 VAPMYYRNANAAILVFDLTQYKTFTEIKSWIQE--LHRNVQDP--MILTLVGNKMDMQ-AQRAVS 131
            :...:||.|:..:||||:|...||..:.||..|  :..:.:||  ....::|||:|:: .|.|..
Human    73 LGVAFYRGADCCVLVFDVTAPNTFKTLDSWRDEFLIQASPRDPENFPFVVLGNKIDLENRQVATK 137

  Fly   132 REEAFVFATSIGATYFETSTETDQGLEQVFISTAQGLVRLADE 174
            |.:|:.::.: ...|||||.:....:||.|.:.|:..::...|
Human   138 RAQAWCYSKN-NIPYFETSAKEAINVEQAFQTIARNALKQETE 179

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
RabX1	NP_524713.1	Rab	7..166	CDD:206640	57/163 (35%)
RAB7A	NP_004628.4	Rab7	9..179	CDD:206655	58/171 (34%)
		Switch 1. /evidence=ECO:0000269|PubMed:15933719, ECO:0007744|PDB:1T91, ECO:0007744|PDB:1YHN	28..41		1/14 (7%)
		Switch 2. /evidence=ECO:0000269|PubMed:15933719, ECO:0007744|PDB:1T91, ECO:0007744|PDB:1YHN	67..82		5/14 (36%)