Protein Alignment RabX1 and RAB6A

DIOPT Version :10

• Sequence 1: NP_524713.1
• Gene: RabX1 / 44172
• FlyBaseID: FBgn0015372
• Length: 261
• Species: Drosophila melanogaster
• Sequence 2: NP_002860.2
• Gene: RAB6A / 5870
• HGNCID: 9786
• Length: 208
• Species: Homo sapiens
• Alignment Length: 178
• Identity: 59/178 - (33%)
• Similarity: 99/178 - (55%)
• Gaps: 11/178 - (6%)

  Fly     7 KVLVLGSRGVGKTRLVIRYIKNTLHRKESEVPTIAVSFFTCNIILDEVKIKLQIWDTAGQERYRA 71
            |::.||.:.||||.|:.|::.::.  ..:...||.:.|.:..:.|::..|:||:||||||||:|:
Human    15 KLVFLGEQSVGKTSLITRFMYDSF--DNTYQATIGIDFLSKTMYLEDRTIRLQLWDTAGQERFRS 77

  Fly    72 VAPMYYRNANAAILVFDLTQYKTFTEIKSWIQELHRNVQDPMILTLVGNKMDMQAQRAVSREEAF 136
            :.|.|.|::.||::|:|:|...:|.:...||.::.......:|:.|||||.|:..:|.||.||..
Human    78 LIPSYIRDSAAAVVVYDITNVNSFQQTTKWIDDVRTERGSDVIIMLVGNKTDLADKRQVSIEEGE 142

  Fly   137 VFATSIGATYFETSTETDQGLEQVFISTAQGLVRLADEGKSPSLRSFQ 184
            ..|..:...:.|||.:....::|:|...|..|         |.:.|.|
Human   143 RKAKELNVMFIETSAKAGYNVKQLFRRVAAAL---------PGMESTQ 181

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
RabX1	NP_524713.1	Rab	7..166	CDD:206640	54/158 (34%)
RAB6A	NP_002860.2	Rab6	14..174	CDD:206654	55/160 (34%)
		Switch 1. /evidence=ECO:0000269|PubMed:19141279, ECO:0007744|PDB:3CWZ	32..50		3/19 (16%)
		Switch 2. /evidence=ECO:0000269|PubMed:19141279, ECO:0007744|PDB:3CWZ	69..88		10/18 (56%)