DRSC/TRiP Functional Genomics Resources

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Protein Alignment RabX1 and RAB1A

DIOPT Version :10

Sequence 1:NP_524713.1 Gene:RabX1 / 44172 FlyBaseID:FBgn0015372 Length:261 Species:Drosophila melanogaster
Sequence 2:NP_004152.1 Gene:RAB1A / 5861 HGNCID:9758 Length:205 Species:Homo sapiens


Alignment Length:159 Identity:66/159 - (41%)
Similarity:97/159 - (61%) Gaps:2/159 - (1%)


- Green bases have known domain annotations that are detailed below.


  Fly     7 KVLVLGSRGVGKTRLVIRYIKNTLHRKESEVPTIAVSFFTCNIILDEVKIKLQIWDTAGQERYRA 71
            |:|::|..||||:.|::|:..:|.  .||.:.||.|.|....|.||...|||||||||||||:|.
Human    13 KLLLIGDSGVGKSCLLLRFADDTY--TESYISTIGVDFKIRTIELDGKTIKLQIWDTAGQERFRT 75

  Fly    72 VAPMYYRNANAAILVFDLTQYKTFTEIKSWIQELHRNVQDPMILTLVGNKMDMQAQRAVSREEAF 136
            :...|||.|:..|:|:|:|..::|..:|.|:||:.|...:.:...|||||.|:..::.|....|.
Human    76 ITSSYYRGAHGIIVVYDVTDQESFNNVKQWLQEIDRYASENVNKLLVGNKCDLTTKKVVDYTTAK 140

  Fly   137 VFATSIGATYFETSTETDQGLEQVFISTA 165
            .||.|:|..:.|||.:....:||.|::.|
Human   141 EFADSLGIPFLETSAKNATNVEQSFMTMA 169

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
RabX1NP_524713.1 Rab 7..166 CDD:206640 66/159 (42%)
RAB1ANP_004152.1 Rab1_Ypt1 10..175 CDD:206661 66/159 (42%)
Switch 1. /evidence=ECO:0000269|PubMed:22416225, ECO:0007744|PDB:3SFV, ECO:0007744|PDB:3TKL 34..48 6/15 (40%)
Switch 2. /evidence=ECO:0000269|PubMed:22416225, ECO:0007744|PDB:3SFV, ECO:0007744|PDB:3TKL 66..83 10/16 (63%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 178..205
Blue background indicates that the domain is not in the aligned region.

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