Protein Alignment RabX1 and RAB20

DIOPT Version :10

• Sequence 1: NP_524713.1
• Gene: RabX1 / 44172
• FlyBaseID: FBgn0015372
• Length: 261
• Species: Drosophila melanogaster
• Sequence 2: NP_060287.1
• Gene: RAB20 / 55647
• HGNCID: 18260
• Length: 234
• Species: Homo sapiens
• Alignment Length: 236
• Identity: 59/236 - (25%)
• Similarity: 98/236 - (41%)
• Gaps: 53/236 - (22%)

  Fly     1 MRGIEGKVLVLGSRGVGKTRLVIRYIKNTLHRKESEVPTIAVSFFTCNIILDEVKIKLQIWDTAG 65
            ||..:.|:::||...||||.|:.||::   .|....|.|:..:|:    :.......:.||||||
Human     1 MRKPDSKIVLLGDMNVGKTSLLQRYME---RRFPDTVSTVGGAFY----LKQWRSYNISIWDTAG 58

  Fly    66 QERYRAVAPMYYRNANAAILVFDLTQYKTFTEIKSWIQELHRNVQDPMILTLVGNKMDMQAQRAV 130
            :|::..:..||.|.|.|.||.:|:...::..|::.....|........:..:||||:|:..:.|:
Human    59 REQFHGLGSMYCRGAAAIILTYDVNHRQSLVELEDRFLGLTDTASKDCLFAIVGNKVDLTEEGAL 123

  Fly   131 SREEAFVFATSIGATYFETSTETDQG-------LEQVFISTAQGL------VRLADEGKSPSLRS 182
            :.:|.           .|.|...|.|       .:||.:..|..|      .::.||...|:...
Human   124 AGQEK-----------EECSPNMDAGDRVSPRAPKQVQLEDAVALYKKILKYKMLDEQDVPAAEQ 177

  Fly   183 --FQSTDSLAYTNTNTAF-------------------SHTV 202
              |:::....| |.:..|                   ||||
Human   178 MCFETSAKTGY-NVDLLFETLFDLVVPMILQQRAERPSHTV 217

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
RabX1	NP_524713.1	Rab	7..166	CDD:206640	44/165 (27%)
RAB20	NP_060287.1	Rab20	6..233	CDD:133326	57/231 (25%)
		Switch 1. /evidence=ECO:0000250|UniProtKB:P62820	28..41		3/12 (25%)
		Switch 2. /evidence=ECO:0000250|UniProtKB:P62820	55..72		7/16 (44%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	125..144		5/29 (17%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	212..234		4/6 (67%)