Protein Alignment RabX1 and RAB8A

DIOPT Version :10

• Sequence 1: NP_524713.1
• Gene: RabX1 / 44172
• FlyBaseID: FBgn0015372
• Length: 261
• Species: Drosophila melanogaster
• Sequence 2: NP_005361.2
• Gene: RAB8A / 4218
• HGNCID: 7007
• Length: 207
• Species: Homo sapiens
• Alignment Length: 175
• Identity: 63/175 - (36%)
• Similarity: 100/175 - (57%)
• Gaps: 5/175 - (2%)

  Fly     7 KVLVLGSRGVGKTRLVIRYIKNTLHRKESEVPTIAVSFFTCNIILDEVKIKLQIWDTAGQERYRA 71
            |:|::|..|||||.::.|:.::..:  .:.:.||.:.|....|.||..:|||||||||||||:|.
Human    10 KLLLIGDSGVGKTCVLFRFSEDAFN--STFISTIGIDFKIRTIELDGKRIKLQIWDTAGQERFRT 72

  Fly    72 VAPMYYRNANAAILVFDLTQYKTFTEIKSWIQELHRNVQDPMILTLVGNKMDMQAQRAVSREEAF 136
            :...|||.|...:||:|:|..|:|..|::||:.:..:....:...::|||.|:..:|.||:|...
Human    73 ITTAYYRGAMGIMLVYDITNEKSFDNIRNWIRNIEEHASADVEKMILGNKCDVNDKRQVSKERGE 137

  Fly   137 VFATSIGATYFETSTETDQGLEQVFISTAQGLVRLAD---EGKSP 178
            ..|...|..:.|||.:.:..:|..|.:.|:.:....|   ||.||
Human   138 KLALDYGIKFMETSAKANINVENAFFTLARDIKAKMDKKLEGNSP 182

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
RabX1	NP_524713.1	Rab	7..166	CDD:206640	57/158 (36%)
RAB8A	NP_005361.2	Rab8_Rab10_Rab13_like	6..172	CDD:206659	58/163 (36%)
		Switch 1. /evidence=ECO:0000250|UniProtKB:P62820	31..45		2/15 (13%)
		Switch 2. /evidence=ECO:0000250|UniProtKB:P62820	63..80		10/16 (63%)