DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment RabX1 and Rab5

DIOPT Version :9

Sequence 1:	NP_524713.1	Gene:	RabX1 / 44172	FlyBaseID:	FBgn0015372	Length:	261	Species:	Drosophila melanogaster
Sequence 2:	NP_001259925.1	Gene:	Rab5 / 33418	FlyBaseID:	FBgn0014010	Length:	219	Species:	Drosophila melanogaster

Alignment Length:	189	Identity:	70/189 - (37%)
Similarity:	112/189 - (59%)	Gaps:	8/189 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 KVLVLGSRGVGKTRLVIRYIKNTLHRKESEVPTIAVSFFTCNIILDEVKIKLQIWDTAGQERYRA 71
            |:::||...|||:.||:|::|...|  |.:..||..:|.|..|.:::..:|.:||||||||||.:
  Fly    31 KLVLLGESAVGKSSLVLRFVKGQFH--EYQESTIGAAFLTQTICIEDTVVKFEIWDTAGQERYHS 93

  Fly    72 VAPMYYRNANAAILVFDLTQYKTFTEIKSWIQELHRNVQDPMILTLVGNKMDMQAQRAVSREEAF 136
            :||||||.|.|||:|:|:....:|...|:|::|||:.....:::.|.|||.|:...|.|..:||.
  Fly    94 LAPMYYRGAQAAIVVYDIQNQDSFQRAKTWVKELHKQASPNIVIALAGNKADLSNIRVVEFDEAK 158

  Fly   137 VFATSIGATYFETSTETDQGLEQVFISTAQGLVRLADEGKSPSLRSFQSTDSLAYTNTN 195
            .:|...|..:.|||.:|...:..:|::.|:.|.:  ::|.:....|.:.|.    |.||
  Fly   159 QYAEENGLLFMETSAKTGMNVNDIFLAIAKKLPK--NDGANNQGTSIRPTG----TETN 211

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
RabX1	NP_524713.1	Ras	7..166	CDD:278499	62/158 (39%)
RabX1	NP_524713.1	Rab	7..166	CDD:206640	62/158 (39%)
Rab5	NP_001259925.1	Rab5_related	29..191	CDD:206653	63/161 (39%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45454232
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0092
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24073
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.840