DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment RabX1 and Rab21

DIOPT Version :9

Sequence 1:	NP_524713.1	Gene:	RabX1 / 44172	FlyBaseID:	FBgn0015372	Length:	261	Species:	Drosophila melanogaster
Sequence 2:	NP_001004238.1	Gene:	Rab21 / 299799	RGDID:	1303150	Length:	223	Species:	Rattus norvegicus

Alignment Length:	175	Identity:	69/175 - (39%)
Similarity:	117/175 - (66%)	Gaps:	4/175 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 RGIEGKVLVLGSRGVGKTRLVIRYIKNTLHRKESEVPTIAVSFFTCNIILDEVKIKLQIWDTAGQ 66
            |....||::||...||||.||:||.:|..:.|  .:.|:..||.|..:.:...::.|.|||||||
  Rat    14 RAYSFKVVLLGEGCVGKTSLVLRYCENKFNDK--HITTLQASFLTKKLNIGGKRVNLAIWDTAGQ 76

  Fly    67 ERYRAVAPMYYRNANAAILVFDLTQYKTFTEIKSWIQELHRNVQDPMILTLVGNKMDMQAQRAVS 131
            ||:.|:.|:|||::|.||||:|:|...:|.::|:|::||.:.:.:.:.|.:||||:|::.:|.||
  Rat    77 ERFHALGPIYYRDSNGAILVYDVTDEDSFQKVKNWVKELRKMLGNEICLCIVGNKIDLEKERHVS 141

  Fly   132 REEAFVFATSIGATYFETSTETDQGLEQVFISTAQGLVRLA--DE 174
            .:||..:|.|:||.::.||.:.::|:|::|:...:.::..|  ||
  Rat   142 IQEAESYAESVGAKHYHTSAKQNKGIEELFLDLCKRMIETAQVDE 186

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
RabX1	NP_524713.1	Ras	7..166	CDD:278499	65/158 (41%)
RabX1	NP_524713.1	Rab	7..166	CDD:206640	65/158 (41%)
Rab21	NP_001004238.1	Rab21	18..179	CDD:133323	65/162 (40%)
Rab21	NP_001004238.1	Effector region. /evidence=ECO:0000250	46..54		1/7 (14%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1226895at2759
OrthoFinder	1	1.000	-	-		FOG0006095
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X4390
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.920