| Sequence 1: | NP_477075.2 | Gene: | sw / 44160 | FlyBaseID: | FBgn0003654 | Length: | 663 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_443076.2 | Gene: | DYNC2I2 / 89891 | HGNCID: | 28296 | Length: | 536 | Species: | Homo sapiens |
| Alignment Length: | 478 | Identity: | 111/478 - (23%) |
|---|---|---|---|
| Similarity: | 185/478 - (38%) | Gaps: | 115/478 - (24%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 179 GLEWEDEFTDDEESSLQNLGNGFTSKLPPGYLTHGLPTVKDVAPAITPLEIKKETEVKKEVNELS 243
Fly 244 EEQKQMIILSENFQRFVVRAGRVIERALSENVDIYTDYIGGGDSEEANDERSHARLSLNRVF--Y 306
Fly 307 DERWSKNRCITSMDWSTHFPELVVGSYHNNEESPNEPDGV-------------------VMVWN- 351
Fly 352 --TKFKKSTPEDVFHCQSAVMSTCFAKFNPNLILGGTYSGQIVLWDNRVQKRTPIQRTPLSAAAH 414
Fly 415 THPVYCLQMV-----GTQNAHNVISISSDGKLCSW--------------SLDMLSQPQDT-LELQ 459
Fly 460 QRQSKAIAITSMAFPANEINSLVMGSEDGYVYSASRHG-------------LRSGVNEVYERHLG 511
Fly 512 PITGISTHYNQLSPDFGHLFLTSSIDWTIKLWSLKDTKPLYSFEDNSDYVMDVAWSPVHPALFAA 576
Fly 577 VDGSGRLDLWNLNQDTEVPTASI 599 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| sw | NP_477075.2 | Dynein_IC2 | 107..135 | CDD:402922 | |
| WD40 | 316..632 | CDD:421866 | 87/339 (26%) | ||
| WD40 repeat | 316..365 | CDD:293791 | 11/70 (16%) | ||
| WD40 repeat | 371..409 | CDD:293791 | 11/37 (30%) | ||
| WD40 repeat | 418..457 | CDD:293791 | 14/58 (24%) | ||
| WD40 repeat | 469..555 | CDD:293791 | 25/98 (26%) | ||
| WD40 repeat | 561..599 | CDD:293791 | 15/37 (41%) | ||
| WD40 repeat | 607..633 | CDD:293791 | |||
| DYNC2I2 | NP_443076.2 | DYNLL2 binding. /evidence=ECO:0000269|PubMed:30649997 | 80..93 | 2/12 (17%) | |
| WD40 | 106..516 | CDD:225201 | 98/407 (24%) | ||
| DYNLRB1 binding. /evidence=ECO:0000269|PubMed:30649997 | 106..131 | 7/46 (15%) | |||
| WD40 repeat | 164..215 | CDD:293791 | 8/50 (16%) | ||
| WD 1. /evidence=ECO:0000255 | 215..255 | 12/39 (31%) | |||
| WD40 | 217..515 | CDD:295369 | 76/267 (28%) | ||
| WD40 repeat | 220..264 | CDD:293791 | 13/43 (30%) | ||
| WD 2. /evidence=ECO:0000255 | 264..308 | 13/45 (29%) | |||
| WD40 repeat | 270..325 | CDD:293791 | 13/54 (24%) | ||
| WD40 repeat | 337..389 | CDD:293791 | 9/51 (18%) | ||
| WD 3. /evidence=ECO:0000255 | 390..430 | 15/44 (34%) | |||
| WD40 repeat | 396..432 | CDD:293791 | 12/40 (30%) | ||
| WD 4. /evidence=ECO:0000255 | 433..473 | 14/39 (36%) | |||
| WD40 repeat | 438..476 | CDD:293791 | 15/37 (41%) | ||
| WD 5. /evidence=ECO:0000255 | 480..520 | ||||
| WD40 repeat | 485..512 | CDD:293791 | |||
| Blue background indicates that the domain is not in the aligned region. | |||||
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 0 | 0.000 | Not matched by this tool. | |||
| Domainoid | 0 | 0.000 | Not matched by this tool. | |||
| eggNOG | 1 | 0.900 | - | - | E1_KOG1587 | |
| Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
| Isobase | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 0 | 0.000 | Not matched by this tool. | |||
| OrthoDB | 1 | 1.010 | - | - | D1453532at2759 | |
| OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
| OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
| orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
| Panther | 0 | 0.000 | Not matched by this tool. | |||
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 0 | 0.000 | Not matched by this tool. | |||
| SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
| SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
| TreeFam | 0 | 0.000 | Not matched by this tool. | |||
| User_Submission | 0 | 0.000 | Not matched by this tool. | |||
| 3 | 2.820 | |||||