Protein Alignment sw and dnai1.1

DIOPT Version :10

• Sequence 1: NP_477075.2
• Gene: sw / 44160
• FlyBaseID: FBgn0003654
• Length: 663
• Species: Drosophila melanogaster
• Sequence 2: XP_073791280.1
• Gene: dnai1.1 / 570363
• ZFINID: ZDB-GENE-040910-7
• Length: 583
• Species: Danio rerio
• Alignment Length: 614
• Identity: 121/614 - (19%)
• Similarity: 246/614 - (40%)
• Gaps: 123/614 - (20%)

  Fly    89 PDASLQATV------NGQ-------SGGKKQPLNLSVYNVQATNI-PPKETLVYTKQTQTTSTGG 139
            ||..::.::      .||       .|.|.:.|...:.....|.| ||:|....|:
Zfish    49 PDIEIEGSLVHKDSEEGQILCAEKEVGRKSKTLFSCITTATQTTINPPREVACQTE--------- 104

  Fly   140 GNGDVLSCHSSPL----SGYMEDWWRPRKAHATDYYDEYNLNPGLEWEDEFTDDEESSLQNLGNG 200
                     |.||    |.....|         :.||.|.............|::|:.:.....|
Zfish   105 ---------SQPLLVNYSATANQW---------EIYDFYQEELQKRTSSTKKDEKENEIAEGAEG 151

  Fly   201 FTSKLPPGYLTHG-LPTVKDVAPAITPLEIKKETEVKKEVNELSEEQKQMIILSENFQRFVVRAG 264
                      .|| |..::|..                     .:....:.:||        .|.
Zfish   152 ----------VHGNLSLLRDFT---------------------DKSDHDLAMLS--------TAA 177

  Fly   265 RVIERALSENV--DIYTDYIGGGDSEEANDERSHARLSLNRVFYDERWSKNRCITSMDWSTHFPE 327
            :::|.|::||:  ||..|:....|  ||::.|......|....:.....|:..::::.|:..:.:
Zfish   178 KLLEYAVNENINGDIIADFKHFED--EADEFRGDKGTLLPLWEFQYNKVKSLPVSALCWNKKYND 240

  Fly   328 LV---VGSYHNNEESPNEPDGVVMVWNTKFKKSTPEDVFHCQSAVMSTCFAKFNPNLILGGTYSG 389
            |.   :||:...|....     ::::.|....:.||.:|:..|.||.....:...:|:..|.::|
Zfish   241 LFAVGLGSHKFTELECG-----MLLFYTWRNNNHPEFLFNTDSGVMCVDIHEQKSHLVAVGLFNG 300

  Fly   390 QIVLWDNRVQKRTPIQRTPLSAAAHTHPVYCLQ-----MVGTQNAHNVISISSDGKLCSWSL--- 446
            .:.:::...:...||..:..|:..|:..|:.::     :.|.   |...|:|:||::.||:|
Zfish   301 NVCVYNLMAKGDQPIYNSMASSGKHSGTVWQVKWWEDDLYGN---HTFFSVSADGRVVSWTLGKY 362

  Fly   447 DMLS------QPQDTLELQQRQSKAIAITSMAFPANEINSLVMGSEDGYVYSASRHGLRSGVNEV 505
            ::.|      .|.|.:..........|..::.|...:....::|:|.|.::..|.|..|  ..:.
Zfish   363 ELFSTNIIKLPPMDKVPDDLNNVIVTAGLTLDFHKQKPYHFLVGTEAGKIHKGSTHYTR--FIKT 425

  Fly   506 YERHLGPITGISTHYNQLSPDFGHLFLTSSIDWTIKLWSLKDTKPLYSFEDNSDYVMDVAWSPVH 570
            ||.|...::.:  .:|..:|   .:|:|..:||.:.:|......|:::|:..|. ||||||:|..
Zfish   426 YEAHFRMVSCV--RWNPFNP---KVFITCGMDWRVNIWDETTDSPVFTFDLKSS-VMDVAWAPYS 484

  Fly   571 PALFAAVDGSGRLDLWNLNQDT-EVPTASIVVAGAPALNRVSWTPSGLHVCIGDEAGKLYVYDVA 634
            ..:||||...|::.:::|:.:. |......||:....|..:.:.|....:.:|::.|.:....::
Zfish   485 STVFAAVTADGKVHVFDLSINRFEALCQQRVVSTKRHLTCIEFNPVHPIIIVGNDRGLVISLKLS 549

  Fly   635 ENLAQPSRDEWSRFNTHLSEIKMNQSDEV 663
            .||.:..::|..:..:..:|:::.:.:::
Zfish   550 PNLRKNPKEEKGKEPSTGAEVEIAKMEKL 578

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
sw	NP_477075.2	Dynein_IC2	105..135	CDD:463291	7/30 (23%)
		WD40	316..632	CDD:475233	73/333 (22%)
		WD40 repeat	316..365	CDD:293791	9/51 (18%)
		WD40 repeat	371..409	CDD:293791	5/37 (14%)
		WD40 repeat	418..457	CDD:293791	13/52 (25%)
		WD40 repeat	469..555	CDD:293791	18/85 (21%)
		WD40 repeat	561..599	CDD:293791	14/38 (37%)
		WD40 repeat	607..633	CDD:293791	4/25 (16%)
dnai1.1	XP_073791280.1	None