Protein Alignment sw and dnai4

DIOPT Version :10

• Sequence 1: NP_477075.2
• Gene: sw / 44160
• FlyBaseID: FBgn0003654
• Length: 663
• Species: Drosophila melanogaster
• Sequence 2: NP_001018595.1
• Gene: dnai4 / 553797
• ZFINID: ZDB-GENE-050522-322
• Length: 778
• Species: Danio rerio
• Alignment Length: 690
• Identity: 152/690 - (22%)
• Similarity: 256/690 - (37%)
• Gaps: 188/690 - (27%)

  Fly    59 SSLGVAPVSEVLSSLSSVNSMTSDNSNTQTPDASLQATVNGQSGGKKQPLNLSVYNVQATNIPPK 123
            |..|.|..|.:        |.|:::...:|.|..:           ||.|:.|:.::|:....||
Zfish   132 SFFGSASASRI--------SQTAESVTDETKDLLV-----------KQDLSNSISDIQSHREEPK 177

  Fly   124 ETL----------VYTKQTQT-------------------------------------------- 134
            |.|          .|..:|:|
Zfish   178 EQLRENILDSTANCYLSETETIWLLDIPAVSVSLESEDAEAVKERNNAYTELCKNRQGNDKYVER 242

  Fly   135 ---TSTGGGNGDVLSCHSSPL--SGYMEDWWRPRKAHATDYYDEYN------LNPGLEWEDEFTD 188
               |.:.......:.|.|..:  ...|...|        |.||.:|      .|..:..|.....
Zfish   243 SMQTFSDAPKTKEVQCDSITMVDKAVMCTVW--------DMYDSFNNISDVSANTVVSSERHEAT 299

  Fly   189 DEESSLQNLGNGFTSKLPPGYLTHGLPTVKDVAPAITPLEIK-KETEVKKE--VNELSEE-QKQM 249
            ..|||            |.|:|.|...:.:.::...|...:. ..|.::|.  |..|.|| ..|:
Zfish   300 IPESS------------PEGHLVHPKRSNQSLSVVSTVSTVSGSSTHIEKMACVLPLDEEPDLQL 352

  Fly   250 IILSENFQRFVVRAGRVI-------ERALSENVDIYTD-----YIGGGDSEEANDERSHARLSLN 302
            |:.|:..::.:....||:       :.|....:.|..|     .:...:|.....:.||.
Zfish   353 ILQSDKLKQDLALMERVVLANVFQPKLAAYRQLPIIEDPDCVQMVMEEESWTEQSKNSHC----- 412

  Fly   303 RVFYDERW------SKNRCITSMDWSTHFPELVVGSYHNNE-ESPNEPDGVVMVWNTKFKKSTPE 360
             .|.:..|      :..|.:|.|.|:...|:|:...|...| ::||  .|:|..|:.| ..:.|:
Zfish   413 -PFLERLWDFSCELTMGRNVTCMVWNKKNPDLLAVGYGQVEFKNPN--SGLVCCWSLK-NPTWPD 473

  Fly   361 DVFHCQSAVMSTCFAKFNPNLILGGTYSGQIVLWDNRVQKRTPIQRTPLSAAAHTHPVYCLQMV- 424
            .||:|:|.|.:..|:..|.|.:..|.|.|.|.:::.:..::|||..:...|..||.||:.|..:
Zfish   474 RVFYCESGVTALDFSASNANQLAVGMYDGTIAIYNVQTSEQTPITDSSDCANLHTSPVWQLTWID 538

  Fly   425 -----GTQNAHNVISISSDGKLCSW-------SLDMLSQPQDTLELQQRQSKAIAITSMAFPANE 477
                 .......::|:||||::..|       .:|::......|:.:|..|.........|..|:
Zfish   539 HEDGLAADKGEILVSVSSDGRISKWIHYKSMECVDLMKLKIHDLQWKQHISSLTPGMCFDFHPND 603

  Fly   478 INSLVMGSEDGYVYSASRHGLRSGVNE----VYERHLGPITGISTHYNQLSPDFGHLFLTSSIDW 538
            ....::|:|:|:::..|     |..||    .|:.|..|:..::     .||....:||:.|.||
Zfish   604 SKIYLVGTEEGHIHKCS-----SSYNEQYLDSYKAHKRPVYKVT-----WSPFCSDVFLSCSSDW 658

  Fly   539 TIKLWSLKDTKPLYSFEDNSDYVMDVAWSPVHPALFAAVDGSGRLDLWNLNQDTEVPTASIVVAG 603
            ||:||......|:..|......|.|:.|||....:|.|| ..|::::|:|...:..||.
Zfish   659 TIQLWRQDLQIPVMGFTSGQRVVFDIMWSPHCATVFGAV-SEGKVEIWDLRVSSLDPTL------ 716

  Fly   604 APALNRVSWTPSGLH------------VCIGDEAGKLYVY 631
                  |:||..|::            |.:||..|::.||
Zfish   717 ------VNWTSPGVNPTALLFSPETDCVLVGDSEGQVTVY 750

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
sw	NP_477075.2	Dynein_IC2	105..135	CDD:463291	12/86 (14%)
		WD40	316..632	CDD:475233	93/346 (27%)
		WD40 repeat	316..365	CDD:293791	16/49 (33%)
		WD40 repeat	371..409	CDD:293791	10/37 (27%)
		WD40 repeat	418..457	CDD:293791	9/51 (18%)
		WD40 repeat	469..555	CDD:293791	24/89 (27%)
		WD40 repeat	561..599	CDD:293791	13/37 (35%)
		WD40 repeat	607..633	CDD:293791	10/37 (27%)
dnai4	NP_001018595.1	WD40 repeat	431..473	CDD:293791	13/44 (30%)
		WD 1. /evidence=ECO:0000255	477..517		11/39 (28%)
		WD40	479..751	CDD:475233	76/295 (26%)
		WD40 repeat	483..526	CDD:293791	11/42 (26%)
		WD 2. /evidence=ECO:0000255	526..573		11/46 (24%)
		WD40 repeat	531..576	CDD:293791	9/44 (20%)
		WD 3. /evidence=ECO:0000255	586..629		11/47 (23%)
		WD40 repeat	589..624	CDD:293791	8/39 (21%)
		WD 4. /evidence=ECO:0000255	633..673		14/44 (32%)
		WD40 repeat	638..675	CDD:293791	12/41 (29%)
		WD 5. /evidence=ECO:0000255	676..715		11/39 (28%)
		WD40 repeat	681..707	CDD:293791	10/26 (38%)
		WD 6. /evidence=ECO:0000255	721..760		7/30 (23%)