Protein Alignment sw and Dnai4

DIOPT Version :10

• Sequence 1: NP_477075.2
• Gene: sw / 44160
• FlyBaseID: FBgn0003654
• Length: 663
• Species: Drosophila melanogaster
• Sequence 2: NP_001019957.1
• Gene: Dnai4 / 313417
• RGDID: 1311027
• Length: 803
• Species: Rattus norvegicus
• Alignment Length: 596
• Identity: 132/596 - (22%)
• Similarity: 230/596 - (38%)
• Gaps: 135/596 - (22%)

  Fly   127 VYTKQTQTTSTGGGNGDVLSCHSSPL--SGYMEDWWRPRKAHATDYYDEYNLNPGLEWEDEFTDD 189
            :|.::...|..|......:.|....:  .|.|...|        |.||.:|:
  Rat   245 LYVERMMQTFNGAPKNKDVQCDKIIMEEKGVMATTW--------DLYDSFNI------------- 288

  Fly   190 EESSLQNLGNGFTSKLPPGYLTHGLPTVKDVAPAITPLEIKK----ETEVKKEVNELSEEQKQMI 250
            .|:||        :.....||:.....|:|..|.|...|...    |:.:..:.:|..|:..:.|
  Rat   289 PEASL--------AAKRSAYLSKASLLVRDRDPKIQDSESSSLMDIESVILAKSHEDEEDNSEKI 345

  Fly   251 ILSENFQRFVVRAGRVIERALSENV-----------DIYTDYIGGGDSE---------------- 288
            :.|:...:.:.    .:||.|.|||           .||.:...|...|
  Rat   346 LKSDKLHQDLF----YMERVLMENVFQPKLAAYRQLPIYKELEPGQPEEDLQVVNKVTEDEVKKD 406

  Fly   289 -----------EANDERSHARLSLNRVFYDERWS------KNRCITSMDWSTHFPELVVGSYHNN 336
                       |...|:|....:|.|:     ||      |...::|:.|:....:|:...| .|
  Rat   407 EEEEMETELEIEITTEQSTIPANLERL-----WSFSCDLTKGLNVSSLSWNKANSDLLAVGY-GN 465

  Fly   337 EESPNEPDGVVMVWNTKFKKSTPEDVFHCQSAVMSTCFAKFNPNLILGGTYSGQIVLWDNRVQKR 401
            .....:..|:...|:.| ....||.::.....|.|..|:..:|||:..|.::|.:.:::.:....
  Rat   466 FGFKEQKRGMACCWSIK-NPMWPERIYQSPYGVTSVDFSISSPNLLAVGYHNGTVAIYNVQSNHN 529

  Fly   402 TPIQRTPLSAAAHTHPVYCLQMV-------GTQNAHNVISISSDGKLCSWSLDMLSQPQDTLELQ 459
            ||:..:..|...|..||:.:|.:       |......::|||:||::..|.:.......|.:.|:
  Rat   530 TPVLDSSESPQKHLGPVWQVQWIEQDRGTTGDDRREILVSISADGRISKWVIRKGLDCHDLMHLK 594

  Fly   460 -----------QRQSKAIAITS-------MAFPANEINSLVMGSEDGYVYSASRHGLRSGVN--- 503
                       :::.|..|:.|       .||...:.|..:.|:|:|.::..|     ...|
  Rat   595 RTTVTSSKKGIEKEKKGEALISRQAPGMCFAFHTKDTNIYLAGTEEGLIHKCS-----CSYNEQY 654

  Fly   504 -EVYERHLGPITGISTHYNQLSPDFGHLFLTSSIDWTIKLWSLKDTKPLYSFEDNSDYVMDVAWS 567
             |.|..|.||:..::  :|...||   :||:.|.||.:.:|...:.||.::|...:..|.|||||
  Rat   655 LETYRGHKGPVYKVT--WNPFCPD---VFLSCSADWGVMIWHQDNVKPFFTFYPTTYVVYDVAWS 714

  Fly   568 PVHPALFAAVDGSGRLDLWNLNQDTEVPTASIVVAGAPAL--NRVSWTPSGLHVCIGDEAGKLYV 630
            |....:|||.: ..|:::|:|...|..|.  ||....|.:  ..|.:......:.:||..|::.|
  Rat   715 PKSAYIFAAAN-ENRVEIWDLQISTLDPL--IVNVANPGIKFTTVLFAKQTDCLLVGDSDGQVAV 776

  Fly   631 YDVAENLAQPS 641
            |:: .|:..|:
  Rat   777 YEL-RNMPTPT 786

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
sw	NP_477075.2	Dynein_IC2	105..135	CDD:463291	1/7 (14%)
		WD40	316..632	CDD:475233	85/346 (25%)
		WD40 repeat	316..365	CDD:293791	10/48 (21%)
		WD40 repeat	371..409	CDD:293791	9/37 (24%)
		WD40 repeat	418..457	CDD:293791	10/45 (22%)
		WD40 repeat	469..555	CDD:293791	25/96 (26%)
		WD40 repeat	561..599	CDD:293791	15/37 (41%)
		WD40 repeat	607..633	CDD:293791	6/27 (22%)
Dnai4	NP_001019957.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..41
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	88..109
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	143..163
		WD40 repeat	447..492	CDD:293791	10/46 (22%)
		WD 1. /evidence=ECO:0000255	492..532		9/39 (23%)
		WD40	496..778	CDD:475233	75/294 (26%)
		WD40 repeat	497..541	CDD:293791	11/43 (26%)
		WD 2. /evidence=ECO:0000255	541..589		11/47 (23%)
		WD40 repeat	547..616	CDD:293791	12/68 (18%)
		WD 3. /evidence=ECO:0000255	616..656		9/44 (20%)
		WD40 repeat	621..659	CDD:293791	9/42 (21%)
		WD 4. /evidence=ECO:0000255	660..700		14/44 (32%)
		WD40 repeat	666..701	CDD:293791	11/39 (28%)
		WD 5. /evidence=ECO:0000255	703..742		14/39 (36%)
		WD40 repeat	708..740	CDD:293791	14/32 (44%)
		WD 6. /evidence=ECO:0000255	748..787		9/40 (23%)
		WD40 repeat	750..779	CDD:293791	6/28 (21%)