DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10939 and SLC9A3R2

DIOPT Version :9

Sequence 1:	NP_524712.1	Gene:	CG10939 / 44155	FlyBaseID:	FBgn0010620	Length:	296	Species:	Drosophila melanogaster
Sequence 2:	XP_016879383.1	Gene:	SLC9A3R2 / 9351	HGNCID:	11076	Length:	372	Species:	Homo sapiens

Alignment Length:	163	Identity:	61/163 - (37%)
Similarity:	86/163 - (52%)	Gaps:	25/163 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 STPTSPKTPTPPTLPP---GVT--------KTCHIVKRPDFDGYGFNLHSEKVKPGQFIGKVDAD 55
            :||.:.....||..||   .|:        :.||:.|.|  .||||||||:|.:|||:|..||..
Human   166 ATPPARAPGAPPRSPPQRLDVSGPLRELRPRLCHLRKGP--QGYGFNLHSDKSRPGQYIRSVDPG 228

  Fly    56 SPAEAAGLKEGDRILEVNGVSIGSETHKQVVARIKAIANEVRLLLIDVDG----KALEVKPASP- 115
            |||..:||:..||::||||.::....|.:|||.|||..:|.|||::|.:.    |.|.|.|...
Human   229 SPAARSGLRAQDRLIEVNGQNVEGLRHAEVVASIKAREDEARLLVVDPETDEHFKRLRVTPTEEH 293

  Fly   116 -----PAAACNGNGSASQNGYE--GTKQEMPGA 141
                 |:...||...|..||..  .::.::||:
Human   294 VEGPLPSPVTNGTSPAQLNGGSACSSRSDLPGS 326

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10939	NP_524712.1	PDZ_signaling	20..101	CDD:238492	41/88 (47%)
SLC9A3R2	XP_016879383.1	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165157323
Domainoid	1	1.000	87	1.000	Domainoid score	I8027
eggNOG	1	0.900	-	-		E1_KOG3528
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D377274at33208
OrthoFinder	1	1.000	-	-		FOG0002256
OrthoInspector	1	1.000	-	-		otm40677
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X2561
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	9	8.710