DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG10939 and Slc9a3r2

DIOPT Version :9

Sequence 1:NP_524712.1 Gene:CG10939 / 44155 FlyBaseID:FBgn0010620 Length:296 Species:Drosophila melanogaster
Sequence 2:NP_075542.2 Gene:Slc9a3r2 / 65962 MGIID:1890662 Length:337 Species:Mus musculus


Alignment Length:350 Identity:101/350 - (28%)
Similarity:142/350 - (40%) Gaps:104/350 - (29%)


- Green bases have known domain annotations that are detailed below.


  Fly    21 KTCHIVKRPDFDGYGFNLHSEKVKPGQFIGKVDADSPAEAAGLKEGDRILEVNGVSIGSETHKQV 85
            :.|.:|:..  .||||:||.||.:.||||.:|:..||||||.|:.|||::|||||::..|||.||
Mouse    10 RLCRLVRGE--QGYGFHLHGEKGRRGQFIRRVEPGSPAEAAALRAGDRLVEVNGVNVEGETHHQV 72

  Fly    86 VARIKAIANEVRLLLIDVD-------------------GKALEVKPASP-PAAACNGN-GS-ASQ 128
            |.||||:..:.:||::|.:                   |......|..| |..||:|: || ..|
Mouse    73 VQRIKAVEGQTQLLVVDKETDEELCRRQLTCTEEMAHRGLPPAHNPWEPKPDWACSGSLGSDTGQ 137

  Fly   129 NGYEGTKQEM-----------PGASANISSISMVSTK--RSSNASSIQSGSTMNASD-------- 172
            ....|..:|:           .|...|:.|......:  ||.:..|..|.|.:.|.|        
Mouse   138 KDVNGPPRELRPRLCHLRRGPQGYGFNLHSDKSRPGQYIRSVDPGSPASHSGLRAQDRLIEVNGQ 202

  Fly   173 ----------------------LDVVD----------RGIPA---VAAPVAITPPPVQNGSKPSS 202
                                  |.|||          |.||.   |..|:   |.||.||:.|:.
Mouse   203 NVEGLRHAEVVARIKAQEDEARLLVVDPETDEHFKRLRVIPTEEHVEGPL---PSPVTNGTSPAQ 264

  Fly   203 PINNNTLMSTPPPPSATKAGINNNGSVYNTNGNGTNGMTTPTTPPPPTSGYKAGTLHLPMTAAEM 267
            ....:...|....|.:.|.  |.:||.:..:             |...||     |||..||||.
Mouse   265 LNGGSVCSSRSDLPGSEKD--NEDGSTWKRD-------------PFQESG-----LHLSPTAAEA 309

  Fly   268 RAKLASKKKYDPKNESVDLKKKFDI 292
            :.| |...:.:.:...:|..:|.:|
Mouse   310 KEK-ARATRVNKRAPQMDWNRKREI 333

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG10939NP_524712.1 PDZ_signaling 20..101 CDD:238492 42/79 (53%)
Slc9a3r2NP_075542.2 PDZ_signaling 9..88 CDD:238492 42/79 (53%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 112..147 10/34 (29%)
PDZ 148..230 CDD:214570 13/81 (16%)
EBP50_C 232..337 CDD:286142 31/125 (25%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 242..337 30/115 (26%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C167847718
Domainoid 1 1.000 86 1.000 Domainoid score I8085
eggNOG 1 0.900 - - E1_KOG3528
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 1 1.050 91 1.000 Inparanoid score I5089
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D377274at33208
OrthoFinder 1 1.000 - - FOG0002256
OrthoInspector 1 1.000 - - otm42750
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 1 1.030 - avgDist Average_Evolutionary_Distance R5127
SonicParanoid 1 1.000 - - X2561
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 1 0.960 - -
1110.790

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