DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10939 and Pdzd2

DIOPT Version :9

Sequence 1:	NP_524712.1	Gene:	CG10939 / 44155	FlyBaseID:	FBgn0010620	Length:	296	Species:	Drosophila melanogaster
Sequence 2:	XP_038959013.1	Gene:	Pdzd2 / 65034	RGDID:	619958	Length:	2818	Species:	Rattus norvegicus

Alignment Length:	311	Identity:	64/311 - (20%)
Similarity:	100/311 - (32%)	Gaps:	90/311 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly    18 GVTKTCHIVK------------------RPDF-----------DGYGFNLHSE----KVKPGQFI 49
            |.::..||||                  ||..           .|.||::...    :.:.|.|:
  Rat   553 GTSQEYHIVKKSTRSLSTTHVESPWRLIRPSVISIIGLYKEKGKGLGFSIAGGRDCIRGQMGIFV 617

  Fly    50 GKVDAD-SPAEAAGLKEGDRILEVNGVSIGSETHKQVVARIKAIANEVRLLLIDVDGKALEVKPA 113
            ..:..: |.||...|||||.||:|||:.|...|.::.:...|.|.:.:.:|.:.....:..:.|.
  Rat   618 KTIFPNGSAAEDGRLKEGDEILDVNGIPIKGLTFQEAIHTFKQIRSGLFVLTVRTKLLSPSLTPC 682

  Fly   114 SPPAAACNGNGSASQNGYEGTK----QEMPGASANISSISMVSTKRSSNASSIQSGSTMNASDLD 174
            |.|......:..:......||.    ||..|:|:       :..|.......|....|:|....
  Rat   683 STPTHMSRSSSPSFNTNSGGTPAGGGQEEGGSSS-------LGRKAPGPKDRIVMEVTLNKEPR- 739

  Fly   175 VVDRGIPAVAAPVAITPPPV--------------QNGSKPSSPINNNT--------------LMS 211
             |..||.|....:..:||.:              .|.|:....:..|:              |..
  Rat   740 -VGLGIGACCLALENSPPGIYIHSLAPGSVAKMESNLSRGDQILEVNSVNVRHAALSKVHAILSK 803

  Fly   212 TPPPPSATKAGINNNGSV---------------YNTNGNGTNGMTTPTTPP 247
            .||.|.....|.:.|..|               .:...|.:.|:.||...|
  Rat   804 CPPGPVRLVIGRHPNPKVSEQEMDEVIARSTYQESREANSSPGLGTPLKSP 854

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10939	NP_524712.1	PDZ_signaling	20..101	CDD:238492	29/114 (25%)
Pdzd2	XP_038959013.1	PDZ_signaling	335..416	CDD:238492
		PDZ_signaling	590..671	CDD:238492	23/80 (29%)
		PDZ_signaling	729..813	CDD:238492	15/85 (18%)
		PHA03247	<985..1446	CDD:223021
		PDZ_signaling	2603..2677	CDD:238492
		PDZ_signaling	2731..2813	CDD:238492
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3528
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900