DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10939 and dlg5a

DIOPT Version :9

Sequence 1:	NP_524712.1	Gene:	CG10939 / 44155	FlyBaseID:	FBgn0010620	Length:	296	Species:	Drosophila melanogaster
Sequence 2:	XP_005156738.1	Gene:	dlg5a / 569065	ZFINID:	ZDB-GENE-030131-3149	Length:	1961	Species:	Danio rerio

Alignment Length:	253	Identity:	55/253 - (21%)
Similarity:	91/253 - (35%)	Gaps:	79/253 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 TSPKTPTPP---------------------TLP----------------PGVTKTCHIVKRPDFD 32
            :||...|||                     |||                |.:.:..:::.....:
Zfish  1328 SSPSLITPPLSPLNLETSSFASSQSQGSISTLPRISVSPVPTEERRKDRPYLEEPRNVMVHKGAE 1392

  Fly    33 GYGFNLHSEKVKPGQFIGKVDADSPAEAAGLKEGDRILEVNGVSIGSETHKQVVARIKAIANEVR 97
            ..|.::.|.: ..|.|:.||...|.|..|||:.||::||.||:::.:.|.:|  ||
Zfish  1393 PLGISIVSGE-NGGIFVSKVTGGSIAHQAGLEYGDQLLEYNGINLRNATEQQ--AR--------- 1445

  Fly    98 LLLIDVDGKALEVKPASPPAAACNGNGSASQNGYEGTKQEMPGASANISSISMVSTKRSSNASSI 162
             |:|......:.:.....|.....||.|.|              |:.:..:|..||.:.|..::.
Zfish  1446 -LIIGQQCDTITIMAQYNPHMYQLGNHSRS--------------SSRLEPVSTQSTPQGSGTATP 1495

  Fly   163 QSGSTMNASDLDVVDRGIPAVAAPVAITPPPVQNGSKPSSPINNNTLMSTPPPPSATK 220
            .:.||::.  |...|.|        .:||     .||.::|..:.......|..|:.|
Zfish  1496 DNHSTIDT--LSEQDEG--------TLTP-----SSKQTTPTTSPNSFIRMPSESSKK 1538

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10939	NP_524712.1	PDZ_signaling	20..101	CDD:238492	22/80 (28%)
dlg5a	XP_005156738.1	CARD	9..88	CDD:260018
		Takusan	128..211	CDD:282652
		Taxilin	295..627	CDD:286771
		RILP-like	338..460	CDD:304877
		SH3BP5	444..648	CDD:283045
		PDZ_signaling	696..783	CDD:238492
		PDZ_signaling	793..866	CDD:238492
		PDZ	1381..1463	CDD:214570	23/94 (24%)
		dbPDZ_assoc	1461..1541	CDD:293216	23/107 (21%)
		PDZ	1541..1623	CDD:214570
		SH3_DLG5	1639..1701	CDD:212794
		Guanylate_kin	1780..1949	CDD:279019
		NK	1794..1950	CDD:302627
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3528
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900