DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10939 and lnx2b

DIOPT Version :9

Sequence 1:	NP_524712.1	Gene:	CG10939 / 44155	FlyBaseID:	FBgn0010620	Length:	296	Species:	Drosophila melanogaster
Sequence 2:	NP_998105.2	Gene:	lnx2b / 564464	ZFINID:	ZDB-GENE-040426-2500	Length:	678	Species:	Danio rerio

Alignment Length:	313	Identity:	69/313 - (22%)
Similarity:	101/313 - (32%)	Gaps:	106/313 - (33%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MSTPTSPKTPTPPTLPPGVTKT---CHIV---------KRPDFDGYGFNLHSEKVKP-GQF-IGK 51
            :|.|:.|.. ..|....|...|   |.:|         :....:..|..:...|..| |.. |.:
Zfish   178 LSAPSEPGL-VNPAFEEGEDDTPLRCSLVAEATVVELFREDPGEDLGLRIVGGKDTPLGNIVIQE 241

  Fly    52 VDADSPAEAAG-LKEGDRILEVNGVSIGSETHKQVVARIKAIANEVRLLLIDVDGKALEVKP--- 112
            :..||.....| |..||.|||||.||:.|.:|.:.:|.|:...:.:||.::...|    .||
Zfish   242 IVRDSLVARDGKLAPGDHILEVNDVSLASISHSRAIAVIRQPCSRLRLTVMQEKG----FKPRPE 302

  Fly   113 ------ASPPAAACNGNGSASQNGYEGTKQEMPGASANISSISMVSTKRSS--NASSIQSGSTMN 169
                  ||||..      |.|.|...||          :..:::|..:||.  ....|:......
Zfish   303 HHTQPSASPPTQ------SPSTNQNHGT----------VIQVTLVKHERSEALGIKLIRKSEEPG 351

  Fly   170 ASDLDVVDRGIPAVAAPVAITPPPVQNGSKPSSPINNNTLMSTPPPPSATKAG-INNNGSVYNTN 233
            ...||::..|:                                     |.|.| :.||..|...|
Zfish   352 VFILDLLPGGL-------------------------------------AAKDGKLRNNDKVLGIN 379

  Fly   234 G----NGTNGMTTPTTPPPPTSGYKAGTLHLPMTAAEMRAKLASKKKYDPKNE 282
            |    :||           |.|..:.      :.|:|||......:..|...|
Zfish   380 GQDLRHGT-----------PESAAQI------IQASEMRVNFVVMRLQDVSEE 415

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10939	NP_524712.1	PDZ_signaling	20..101	CDD:238492	27/95 (28%)
lnx2b	NP_998105.2	RING	46..82	CDD:214546
		PDZ_signaling	210..291	CDD:238492	24/80 (30%)
		PDZ_signaling	325..406	CDD:238492	23/134 (17%)
		PDZ_signaling	451..537	CDD:238492
		PDZ_signaling	587..671	CDD:238492
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3528
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900