DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10939 and pdzd3a

DIOPT Version :9

Sequence 1:	NP_524712.1	Gene:	CG10939 / 44155	FlyBaseID:	FBgn0010620	Length:	296	Species:	Drosophila melanogaster
Sequence 2:	XP_685398.3	Gene:	pdzd3a / 557269	ZFINID:	ZDB-GENE-080430-1	Length:	520	Species:	Danio rerio

Alignment Length:	190	Identity:	52/190 - (27%)
Similarity:	82/190 - (43%)	Gaps:	31/190 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MSTPTSPKTPTPPTLP--PGVTKTCHIVKRPDFDGYGFNLHSEKVKPGQ---FIGKVDADSPAEA 60
            |..|..|.......||  |   ||.|:.:.|  .||||.|..||::.|:   .:.::|..||||.
Zfish   263 MGLPIIPAFAETHNLPYRP---KTLHLTQGP--QGYGFLLRQEKLRSGRIAHILREIDPCSPAET 322

  Fly    61 AGLKEGDRILEVNGVSIGSETHKQVVARIKAIANEVRLLLIDVDGK----ALEVKP--------- 112
            ||:::|:.:|.|||..:....|:.:|::|:....:|.|..|.:.|:    .|.:.|
Zfish   323 AGMEDGEIVLAVNGEQVEDAEHEGIVSKIRQSGQQVTLTTISIAGRDFYTQLAMSPLLFYDEHIP 387

  Fly   113 -----ASPPAAACNGNGSASQNGYEGTKQEMPGASANISSISMVSTKRSSNASSIQSGST 167
                 |:|......|:.:..|.......:|..|...|   :..|..|..:....:.||||
Zfish   388 KCEPFATPALEHPEGHQNPPQPRLCELHKEGTGFGFN---LGCVENKPGTYIGQVVSGST 444

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10939	NP_524712.1	PDZ_signaling	20..101	CDD:238492	29/83 (35%)
pdzd3a	XP_685398.3	PDZ_signaling	61..142	CDD:238492
		PDZ_signaling	172..252	CDD:238492
		PDZ	280..363	CDD:214570	30/87 (34%)
		PDZ	408..490	CDD:214570	10/40 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3528
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D377274at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm26228
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	4	3.820