DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG10939 and lnx2a

DIOPT Version :9

Sequence 1:	NP_524712.1	Gene:	CG10939 / 44155	FlyBaseID:	FBgn0010620	Length:	296	Species:	Drosophila melanogaster
Sequence 2:	NP_001106696.2	Gene:	lnx2a / 553331	ZFINID:	ZDB-GENE-060228-2	Length:	737	Species:	Danio rerio

Alignment Length:	323	Identity:	65/323 - (20%)
Similarity:	106/323 - (32%)	Gaps:	101/323 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly    13 PTLPPGVTKTCHIVKRPDFDGYGFNLHSEKVKP--GQFIGKVDADSPAEAAG-LKEGDRILEVNG 74
            |:||.|...|..:.:...:...|.::......|  ...|.:|..|......| |..||:||:||.
Zfish   261 PSLPEGEITTIEVHRTNPYSEMGISIVGGNETPLINVVIQEVYRDGVIARDGRLLAGDQILQVNN 325

  Fly    75 VSIGSETH---KQVVARIKA-----IANEVRLLLIDVDGKALEVKPASPPAAACNGNGSASQNGY 131
            |.|.:..|   :..:||..|     :..|.|.             .|.||||..:..||.:....
Zfish   326 VDISNVPHNFARSTLARPCATLQLTVLRERRC-------------SARPPAATASPKGSPASIRI 377

  Fly   132 EGTKQEMPGASANISSISMVSTKRSSNA-----SSIQSGSTMNASDLDVVDR-----------GI 180
            ...|:|    |:....|.:|  :|:..|     ..::.|.......|...||           |.
Zfish   378 TLHKRE----SSEQLGIKLV--RRTDEAGVFILDLLEGGLAAKDGRLCSNDRVLAVNEHDLRHGT 436

  Fly   181 PAVAAPVAITPPP-----VQNGSKPSSPINNNTLMS--------TPPPPSATKAGINNNGSVYNT 232
            |.:||.:......     :...||.:..::..:.::        .||.||
Zfish   437 PELAAQIIQASGERVNLLISRSSKQTMAVHTGSTLTRDIWSHDHIPPLPS--------------- 486

  Fly   233 NGNGTNGMTTPTTPPPPTSGYKAGTLHLPMTAAEMRAKLASKKKYDPKNESVDLKKKFDIIQK 295
                     |.|..|.|       :|||..::.:.           ..::.|:.|:|...::|
Zfish   487 ---------TATPSPVP-------SLHLARSSTQR-----------DLSQCVNCKEKHITVKK 522

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10939	NP_524712.1	PDZ_signaling	20..101	CDD:238492	22/91 (24%)
lnx2a	NP_001106696.2	zf-RING_2	49..87	CDD:290367
		PDZ	267..353	CDD:214570	20/85 (24%)
		PDZ_signaling	375..455	CDD:238492	15/85 (18%)
		PDZ_signaling	515..600	CDD:238492	2/8 (25%)
		PDZ_signaling	646..730	CDD:238492
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3528
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900