DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10939 and PDZK1

DIOPT Version :9

Sequence 1:	NP_524712.1	Gene:	CG10939 / 44155	FlyBaseID:	FBgn0010620	Length:	296	Species:	Drosophila melanogaster
Sequence 2:	XP_024303384.1	Gene:	PDZK1 / 5174	HGNCID:	8821	Length:	539	Species:	Homo sapiens

Alignment Length:	151	Identity:	51/151 - (33%)
Similarity:	71/151 - (47%)	Gaps:	26/151 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 PTSPK-----TPTPPTLPPGVTKTCHIVKRPDFDGYGFNLHSEKVKPGQFIGKVDADSPAEAAGL 63
            |:|||     |....|..|   :.|.:.|: :...|||.|..||...|..:..|:..||||.|||
Human     9 PSSPKVLVLTTEMTSTFNP---RECKLSKQ-EGQNYGFFLRIEKDTEGHLVRVVEKCSPAEKAGL 69

  Fly    64 KEGDRILEVNGVSIGSETHKQVVARIKAIANEVRLLLIDVDG--KALEVKPASPPAAACNGNGSA 126
            ::|||:|.:|||.:..|.|.|||..::...|.|.||::|.|.  ||::.:......
Human    70 QDGDRVLRINGVFVDKEEHMQVVDLVRKSGNSVTLLVLDGDSYEKAVKTRVDLKEL--------- 125

  Fly   127 SQNGYEGTKQEMPGASANISS 147
                  |..|:..|.|.||.|
Human   126 ------GQSQKEQGLSDNILS 140

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10939	NP_524712.1	PDZ_signaling	20..101	CDD:238492	33/80 (41%)
PDZK1	XP_024303384.1	PDZ_signaling	27..107	CDD:238492	34/83 (41%)
		PDZ	152..232	CDD:214570
		PDZ_signaling	261..340	CDD:238492
		PDZ	395..475	CDD:214570
		F1-ATPase_gamma	<457..>501	CDD:320933
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3528
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D377274at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm40677
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	4	3.820