DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10939 and Lnx2

DIOPT Version :9

Sequence 1:	NP_524712.1	Gene:	CG10939 / 44155	FlyBaseID:	FBgn0010620	Length:	296	Species:	Drosophila melanogaster
Sequence 2:	NP_001101799.1	Gene:	Lnx2 / 360761	RGDID:	1308222	Length:	686	Species:	Rattus norvegicus

Alignment Length:	204	Identity:	53/204 - (25%)
Similarity:	87/204 - (42%)	Gaps:	28/204 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 STPTSPKTPTPPTLPPGVTK--TC---HI-VKRPDFDGYGFNLHSEK-VKPGQFIGKVDADSP-- 57
            |....|.:.:.|:....:|:  ||   || ||:...:..|..:...: .|.|:....|.:..|
  Rat   437 SNHAQPPSHSRPSSHKDLTRCVTCQEKHITVKKEPHESLGMTVAGGRGSKSGELPIFVTSVPPHG 501

  Fly    58 --AEAAGLKEGDRILEVNGVSIGSETHKQVVARIKAIANEVRLLLIDVDGKALEVKPASPPAAAC 120
              |....:|.||.:|.:||:.:.:.:|.:.||.:||.|....::|     |||||:.|...|.|.
  Rat   502 CLARDGRIKRGDVLLNINGIDLTNLSHSEAVAMLKASAASPAVIL-----KALEVQIAEEAAQAT 561

  Fly   121 NGN-GSASQNGYEGTKQE-------MPGASANISSISMVSTKRSSNASSIQSGSTMNASD----L 173
            ... |:.|:|.|:.:...       :|.|..:...|.:..:...|...||..|...|.|:    :
  Rat   562 EEQPGAFSENEYDASWSPSWVMWLGLPSALHSCHDIVLRRSYLGSWGFSIVGGYEENHSNQPFFI 626

  Fly   174 DVVDRGIPA 182
            ..:..|.||
  Rat   627 KTIVLGTPA 635

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10939	NP_524712.1	PDZ_signaling	20..101	CDD:238492	25/91 (27%)
Lnx2	NP_001101799.1	mRING-HC-C3HC3D_LNX2	46..90	CDD:319694
		PDZ	229..315	CDD:214570
		PDZ	335..421	CDD:214570
		PDZ_signaling	462..538	CDD:238492	20/75 (27%)
		PDZ_signaling	595..679	CDD:238492	10/41 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3528
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900