DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG10939 and pdzk1

DIOPT Version :9

Sequence 1:	NP_524712.1	Gene:	CG10939 / 44155	FlyBaseID:	FBgn0010620	Length:	296	Species:	Drosophila melanogaster
Sequence 2:	NP_001122142.2	Gene:	pdzk1 / 337325	ZFINID:	ZDB-GENE-031222-1	Length:	553	Species:	Danio rerio

Alignment Length:	241	Identity:	63/241 - (26%)
Similarity:	97/241 - (40%)	Gaps:	68/241 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly    15 LPPGVTKTC--HIVKRPDF-------DGYGFNLHSEKVKPGQFIGKVDADSPAEAAGLKEGDRIL 70
            :.|||:...  |:..:|..       |||||.|..:..:.|..||::|..||||.||:|:.||:.
Zfish   217 IQPGVSHATVKHLPHKPRIADMIKRADGYGFMLKEDPKRKGHCIGEIDKGSPAERAGMKDMDRLA 281

  Fly    71 EVNGVSIGSETHKQVVARIKAIANEVRLLLIDVD-GKALEVKPASPPAAACNGNGSASQNGYEGT 134
            .|||..|.:..|:|||.:| ...|:..||::|.: .|..::...||...            :|..
Zfish   282 AVNGEDIENCKHEQVVEKI-CQGNKCCLLVLDAETDKIYKLGGVSPLLY------------WEEM 333

  Fly   135 KQEMPGASANISSISMVSTKRSSNASSIQSGSTMNASDLDVVDRGIPAVAAPVAITPPPVQNGSK 199
            :..:||...|                        .|..:..|...:|  ||.||.||.|....:.
Zfish   334 RGSLPGYPDN------------------------EAVAIPAVAAAVP--AAVVAATPAPAATPAP 372

  Fly   200 PSSPINNNTLMSTPPPPSATKAGINNN-----------GSVYNTNG 234
            .::|        ||.|.:|..|.:::.           |..::.||
Zfish   373 AATP--------TPVPAAAEPADVDHKPKLCRLERTSAGFGFHLNG 410

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10939	NP_524712.1	PDZ_signaling	20..101	CDD:238492	33/89 (37%)
pdzk1	NP_001122142.2	PDZ_signaling	6..86	CDD:238492
		PDZ_signaling	126..204	CDD:238492
		PDZ	232..311	CDD:214570	32/79 (41%)
		PDZ_signaling	392..471	CDD:238492	3/19 (16%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3528
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D377274at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm26228
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	4	3.820