DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10939 and Ush1c

DIOPT Version :9

Sequence 1:	NP_524712.1	Gene:	CG10939 / 44155	FlyBaseID:	FBgn0010620	Length:	296	Species:	Drosophila melanogaster
Sequence 2:	XP_006229284.1	Gene:	Ush1c / 308596	RGDID:	1303329	Length:	910	Species:	Rattus norvegicus

Alignment Length:	193	Identity:	47/193 - (24%)
Similarity:	76/193 - (39%)	Gaps:	44/193 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    46 GQFIGKVDADSPAEAAGLKEGDRILEVNGVSIGSETHKQVVARI---KAIANEVRLL-LIDVDGK 106
            |.||..:.....|::.||:.||.|:.:||.||.|.||::|:..|   |.::.:||.: ||.|...
  Rat   111 GLFISHLIKGGQADSVGLQVGDEIVRINGYSISSCTHEEVINLIRTKKTVSIKVRHIGLIPVKSS 175

  Fly   107 ALEVKPASPPAAACNGNGSASQNGYEGTKQEMPGASANISSISMVSTKRSSNASSIQSGSTMNAS 171
            ..|      |......:...|::|         |....:||....:||......|:
  Rat   176 PEE------PLKWQYVDQFVSESG---------GVRGGLSSPGNRTTKEKKVFISL--------- 216

  Fly   172 DLDVVDRGIPAVAAPVAITPPPVQNGSKPSSPINNNTLMSTPPPPSATKAGINNNGSVYNTNG 234
               |..||:..     :|:..|:|   ||...::|     ..|...:.:.|:.....:...||
  Rat   217 ---VGSRGLGC-----SISSGPIQ---KPGIFVSN-----VKPGSLSAEVGLETGDQIVEVNG 263

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10939	NP_524712.1	PDZ_signaling	20..101	CDD:238492	21/58 (36%)
Ush1c	XP_006229284.1	harmonin_N	2..80	CDD:259819
		PDZ_signaling	85..165	CDD:238492	19/53 (36%)
		PDZ_signaling	209..289	CDD:238492	14/80 (18%)
		Cgr1	<316..>358	CDD:281823
		PDZ_signaling	751..838	CDD:238492
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3528
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900