DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10939 and WHRN

DIOPT Version :9

Sequence 1:	NP_524712.1	Gene:	CG10939 / 44155	FlyBaseID:	FBgn0010620	Length:	296	Species:	Drosophila melanogaster
Sequence 2:	XP_011516787.1	Gene:	WHRN / 25861	HGNCID:	16361	Length:	918	Species:	Homo sapiens

Alignment Length:	157	Identity:	39/157 - (24%)
Similarity:	67/157 - (42%)	Gaps:	31/157 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 STP-TSPKTPTPPTLPPGVTKTCHIVKRPDFDGYGFNLH-SEKVKPGQFIGKVDADSPAEAAGLK 64
            :|| ..|....|.:..||..:...:.:....:|.||::. ..:...|.::..|:..|.||..||:
Human   119 TTPYRQPAWGGPDSAGPGEVRLVSLRRAKAHEGLGFSIRGGSEHGVGIYVSLVEPGSLAEKEGLR 183

  Fly    65 EGDRILEVNGVSIGSETHKQVVARIKAIANEVRLLL--------------------IDVDGKALE 109
            .||:||.||..|:...||.:.|   ||:....:|:|                    :|..|:::
Human   184 VGDQILRVNDKSLARVTHAEAV---KALKGSKKLVLSVYSAGRIPGGYVTNHIYTWVDPQGRSI- 244

  Fly   110 VKPASPPAAACNGNGSASQNGYEGTKQ 136
                |||:.....:|.|.:. .||.::
Human   245 ----SPPSGLPQPHGGALRQ-QEGDRR 266

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10939	NP_524712.1	PDZ_signaling	20..101	CDD:238492	24/101 (24%)
WHRN	XP_011516787.1	HN_L-whirlin_R1_like	37..112	CDD:259822
		PDZ_signaling	138..215	CDD:238492	22/79 (28%)
		PDZ_signaling	277..357	CDD:238492
		HN_L-whirlin_R2_like	419..499	CDD:259823
		PDZ_signaling	827..898	CDD:238492
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3528
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810