DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10939 and Pdzd3

DIOPT Version :9

Sequence 1:	NP_524712.1	Gene:	CG10939 / 44155	FlyBaseID:	FBgn0010620	Length:	296	Species:	Drosophila melanogaster
Sequence 2:	NP_573489.2	Gene:	Pdzd3 / 170761	MGIID:	2429554	Length:	498	Species:	Mus musculus

Alignment Length:	242	Identity:	63/242 - (26%)
Similarity:	99/242 - (40%)	Gaps:	57/242 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly    17 PGVTKTCHIVKRPDFDGYGFNLHSEK---VKPGQFIGKVDADSPAEAAGLKEGDRILEVNGVSIG 78
            |...:..:|.|.|  :|:||.|..||   .:.|||:..||...||:.||:|.|||::.|.|.|:.
Mouse   258 PAKPRCLNIEKGP--EGFGFLLREEKGLDGRLGQFLWDVDPGLPADKAGMKAGDRLVAVAGESVD 320

  Fly    79 SETHKQVVARIKAIANEVRLLLIDVDG----KALEVKP---------ASPPAAACNG---NGSAS 127
            ...|::.|:||:|..:.|.|:::|.:.    ..:.:.|         |:||.|....   ..:..
Mouse   321 GLGHEETVSRIRAQGSCVSLIVVDPEADRFFSMVRLSPLLFLENTEIAAPPLAETKDLPVEDTVE 385

  Fly   128 QNGYEGTKQ----EMPG----------ASANISSISMVSTKRSSNASSIQSGSTMNASDLDVVDR 178
            .:|..|:.|    ..||          ||.....||.|:...|:..:.:|.|.|:    |:|  .
Mouse   386 PSGLAGSCQCFLYPGPGGGYGFRLCCVASGPCLFISQVTPGGSAARAGLQVGDTV----LEV--N 444

  Fly   179 GIPAVAAPVAITPPPVQNGSKPSSPINNNTLMSTPPPPSATKAGINN 225
            |.|...                .|.::....::...||...|.|..|
Mouse   445 GYPVGG----------------DSELDRLQQLTEAEPPLCLKLGARN 475

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10939	NP_524712.1	PDZ_signaling	20..101	CDD:238492	32/83 (39%)
Pdzd3	NP_573489.2	PDZ_signaling	47..127	CDD:238492
		PDZ_signaling	155..232	CDD:238492
		PDZ	260..345	CDD:214570	32/86 (37%)
		PDZ_signaling	407..471	CDD:238492	16/85 (19%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3528
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D377274at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm42750
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.820