Protein Alignment CDNF and Manf

DIOPT Version :10

• Sequence 1: XP_011517790.1
• Gene: CDNF / 441549
• HGNCID: 24913
• Length: 196
• Species: Homo sapiens
• Sequence 2: NP_477445.1
• Gene: Manf / 41983
• FlyBaseID: FBgn0027095
• Length: 173
• Species: Drosophila melanogaster
• Alignment Length: 190
• Identity: 81/190 - (42%)
• Similarity: 112/190 - (58%)
• Gaps: 23/190 - (12%)

Human     7 VAVVAFCAGLLVSHPVLTQGQEAGGRPGADCEVCKEFLNRFYKSLIDRGVNFSLDTIEKELISFC 71
            |.|:.|.|.|..:...|.:         .|||||.:.:.||..|| |.........||.....||
  Fly     7 VVVIGFLATLAQTSLALKE---------EDCEVCVKTVRRFADSL-DDSTKKDYKQIETAFKKFC 61

Human    72 LDTKGKENRLCYYLGATKDAATKILSEVTRPMSVHMPAMKICEKLKKLDSQICELKYGITQPRVF 136
            ...|.||:|.|||||..:::||.||:|:::|:|..|||.||||||||.|:|||:|:|
  Fly    62 KAQKNKEHRFCYYLGGLEESATGILNELSKPLSWSMPAEKICEKLKKKDAQICDLRY-------- 118

Human   137 PKKTLDLASVDLRKMRVAELKQILHSWGEECRACAEKTDYVNLIQELAPKYAATHPKTEL 196
             :|.:||.||||:|::|.:||:||:.|.|.|..|.||.|::..|:||.|||:    ::||
  Fly   119 -EKQIDLNSVDLKKLKVRDLKKILNDWDESCDGCLEKGDFIKRIEELKPKYS----RSEL 173

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CDNF	XP_011517790.1	ARMET_N	36..128	CDD:466306	46/91 (51%)
		ARMET_C	145..187	CDD:462997	21/41 (51%)
Manf	NP_477445.1	ARMET_N	27..122	CDD:466306	48/104 (46%)
		ARMET_C	126..168	CDD:462997	21/41 (51%)