Protein Alignment mAcon1 and ACO1

DIOPT Version :10

• Sequence 1: NP_524708.1
• Gene: mAcon1 / 44149
• FlyBaseID: FBgn0010100
• Length: 787
• Species: Drosophila melanogaster
• Sequence 2: NP_195308.1
• Gene: ACO1 / 829737
• AraportID: AT4G35830
• Length: 898
• Species: Arabidopsis thaliana
• Alignment Length: 859
• Identity: 243/859 - (28%)
• Similarity: 359/859 - (41%)
• Gaps: 188/859 - (21%)

  Fly    74 EKVLYSHLDDPANQDIVRGTSYLRLRPDRVAMQDATAQMALLQF---------ISSGLKKV--AV 127
            ||:|......|...:|       ..:|.||.:||.|...|::..         :.....|:  .|
plant    65 EKILDWENTSPKQVEI-------PFKPARVLLQDFTGVPAVVDLACMRDAMNNLGGDSNKINPLV 122

  Fly   128 PSTVHCDHLIEAQIGGPKDLARAK-----DLNKEVYDFLASTCAKYGLGFW------KPGSGIIH 181
            |..:..||.::..:...::..:|.     ..|||.:.||     |:|...:      .|||||:|
plant   123 PVDLVIDHSVQVDVARSENAVQANMELEFQRNKERFAFL-----KWGSNAFHNMLVVPPGSGIVH 182

  Fly   182 QIILENYA-----FPGLL----MIGTDSHTPNGGGLGGLCIGVGGADAVDVMADIPWELKCPKVI 237
            |:.||..|     ..|||    ::||||||....|||....||||.:|...|...|..:..|.|:
plant   183 QVNLEYLARVVFNTNGLLYPDSVVGTDSHTTMIDGLGVAGWGVGGIEAEATMLGQPMSMVLPGVV 247

  Fly   238 GVNLTGKISGWTSPKDVILKVADILTVKGGTGAIIEYHGKGVDSISCTGMATICNMGAEIGATTS 302
            |..||||:....:..|::|.|..:|...|..|..:|:||:|:..:|....|||.||..|.|||..
plant   248 GFKLTGKLRDGMTATDLVLTVTQMLRKHGVVGKFVEFHGEGMRELSLADRATIANMSPEYGATMG 312

  Fly   303 LFPFNQRMADYLKSTGRA-GIASEAQKYQAKILSADK----------NCEYDELIEINLDTLEPH 356
            .||.:.....||:.|||: ...|..:.|    |.|:|          ...|...:|:||:.:||.
plant   313 FFPVDHVTLQYLRLTGRSDDTVSMIEAY----LRANKMFVDYSEPESKTVYSSCLELNLEDVEPC 373

  Fly   357 VNGPFTPDLGHPISKLGEN---------------------SKK-----NGYPMDIR-----VGLI 390
            |:||..|....|:.::..:                     ||.     ||....:|     :..|
plant   374 VSGPKRPHDRVPLKEMKADWHSCLDNRVGFKGFAVPKEAQSKAVEFNFNGTTAQLRHGDVVIAAI 438

  Fly   391 GSCTNSSYED-MGRCASIAKDAMSHGLKSK--IPFNVTPGSEQIRATIERDGISEVFDKFGGTVL 452
            .||||:|... |...|.:||.|...||:.|  |..::.|||..:...:.:.|:.:..::.|.:::
plant   439 TSCTNTSNPSVMLGAALVAKKACDLGLEVKPWIKTSLAPGSGVVTKYLAKSGLQKYLNQLGFSIV 503

  Fly   453 ANACGPCIGQWDRKDVKKGDKNTI---------VTSYNRNFTGRNDANPATHC-FVTSPELVTAL 507
            ...|..|||  :..|:.:...:.|         |.|.||||.||  .:|.|.. ::.||.||.|.
plant   504 GYGCTTCIG--NSGDIHEAVASAIVDNDLVASAVLSGNRNFEGR--VHPLTRANYLASPPLVVAY 564

  Fly   508 SIAGRLDFNPLTDEL-TGADGKK--FKLKAPFGDE---------LPAKGFDPGQDTYTAPPPSG- 559
            ::||.:|.:..|..: ||.|||:  |:...|...|         ||    |..:.||.|.....
plant   565 ALAGTVDIDFETQPIGTGKDGKQIFFRDIWPSNKEVAEVVQSSVLP----DMFKATYEAITKGNS 625

  Fly   560 --ENVKVAV------DPKSTRLQLLEPFDKWNGQDLT--------DLTVLIKVKGKCTTDHISAA 608
              ..:.||.      |||||.:.  || ..:.|..::        |...|:......||||||.|
plant   626 MWNQLSVASGTLYEWDPKSTYIH--EP-PYFKGMTMSPPGPHGVKDAYCLLNFGDSITTDHISPA 687

  Fly   609 G------PWLKY---RGHLDNISNNMFIGATNYENNEM-------------NNIKNQRNGSWGGV 651
            |      |..||   || :|....|.:  .:...|:|:             .::|.:.......:
plant   688 GSIHKDSPAAKYLMERG-VDRRDFNSY--GSRRGNDEIMARGTFANIRIVNKHLKGEVGPKTVHI 749

  Fly   652 P--------DVARDYKANGIKWVAVGDENYGEGSSREHAALEPRHLGGRAIIVKSFARIHETNLK 708
            |        |.|..|:..|...:.:....||.||||:.||..|..||.:|:|.|||.|||.:||.
plant   750 PTGEKLSVFDAAMKYRNEGRDTIILAGAEYGSGSSRDWAAKGPMLLGVKAVISKSFERIHRSNLV 814

  Fly   709 KQGLLPLTFANPADYDKIQPTSK----ISL-LNLKSLAPGKPVDAEIKNGDKVERIKLNHTL--- 765
            ..|::||.|....|.:.:..|.:    |.| .|:..:.||:.|.....||.     ....||
plant   815 GMGIIPLCFKAGEDAETLGLTGQELYTIELPNNVSEIKPGQDVTVVTNNGK-----SFTCTLRFD 874

  Fly   766 NDLQIGWFKAGSAL 779
            .::::.:|..|..|
plant   875 TEVELAYFDHGGIL 888

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mAcon1	NP_524708.1	aconitase_mito	52..782	CDD:273561	243/859 (28%)
ACO1	NP_195308.1	PLN00070	1..898	CDD:215047	243/859 (28%)