Protein Alignment mAcon1 and Ireb2

DIOPT Version :9

• Sequence 1: NP_001097186.2
• Gene: mAcon1 / 44149
• FlyBaseID: FBgn0010100
• Length: 787
• Species: Drosophila melanogaster
• Sequence 2: XP_038938018.1
• Gene: Ireb2 / 64831
• RGDID: 621539
• Length: 964
• Species: Rattus norvegicus
• Alignment Length: 968
• Identity: 237/968 - (24%)
• Similarity: 368/968 - (38%)
• Gaps: 258/968 - (26%)

  Fly    34 YTASKVALSKFDSDVYLPYEKLNKRLEVVRGRLNRPLTLSEKVLYSHLDDPANQDIVRGTSYLRL 98
            :...|:..:|:|   .||| .:...||......:..|...|.|: :.||....|..|....:
  Rat    27 FNVPKLGGTKYD---ILPY-SIRVLLEAAVRNCDGFLMKKEDVI-NILDWKTKQSNVEVPFF--- 83

  Fly    99 RPDRVAMQDATAQMALLQF---------ISSGLKKV--AVPSTVHCDHLIEAQIG---------- 142
             |.||.:||.|...|::.|         :....|||  |.|:.:..||.::....
  Rat    84 -PARVVLQDFTGIPAMVDFAAMREAVKTLGGDPKKVHPACPTDLTVDHSLQIDFSKCAIQNAPNP 147

  Fly   143 GPKDLARAKDL------------------------------------------------------ 153
            |..||.:|..|
  Rat   148 GGGDLQKAGKLSPLKVQPKKLPCRGQTTCRGSCDSGELSRNSGTFSSQIENTPVLCPFHLQPVPE 212

  Fly   154 --------------NKEVYDFLASTCAKYGLGFWK------PGSGIIHQIILENYA--------- 189
                          |:|...|.     |:..|.:|      ||:|:.||:.||:.:
  Rat   213 PETVLKNQEVEFGRNRERLQFF-----KWSSGAFKNVAVIPPGTGMAHQVNLEHLSRVVFEEADL 272

  Fly   190 -FPGLLMIGTDSHTPNGGGLGGLCIGVGGADAVDVMADIPWELKCPKVIGVNLTGKISGWTSPKD 253
             ||. .:||||||.....|||.|..||||.:...||..:|..|..|:|:|..|||..:.:.:..|
  Rat   273 LFPD-SVIGTDSHITMVNGLGILGWGVGGIETEAVMLGLPVTLTLPEVVGCELTGSSNAFVTSID 336

  Fly   254 VILKVADILTVKGGTGAIIEYHGKGVDSISCTGMATICNMGAEIGATTSLFPFNQRMADYLKSTG 318
            ::|.:...|...|..|..:|:.|.||..:|.....||.||..|.||..|.||.:.....:|:.||
  Rat   337 IVLGITKHLRQVGVAGKFVEFFGSGVSQLSIVDRTTIANMCPEYGAILSFFPVDNVTLRHLEHTG 401

  Fly   319 --RAGIASEAQKYQA-KILSADKNC---EYDELIEINLDTLEPHVNGPFTPD------------- 364
              :..:.|..:..:| |:...|:|.   ||.::|:|||:::...|:||..|.
  Rat   402 FDKTKLESMEEYLKAVKLFRNDENSSEPEYSQVIQINLNSIVASVSGPKRPQDRVAVTDMKSDFQ 466

  Fly   365 --LGHPISKLGEN--SKKNGYPMDIR--------------VGLIGSCTNSSYEDMGRCAS-IAKD 410
              |...:...|..  ::|....:.:|              :..:.||||:....:...|. :||.
  Rat   467 ACLNEKVGFKGFQVAAEKQSDTVSVRYDGSEYKLSHGSVVIAAVISCTNNCNPSVMLAAGLLAKK 531

  Fly   411 AMSHGLKSK--IPFNVTPGSEQIRATIERDGISEVFDKFGGTVLANACGPCIG------QWDRKD 467
            |:..||:.|  |..:::|||..:...:...|:.....|.|..::...|..|:|      :.....
  Rat   532 AVETGLRVKPYIRTSLSPGSGMVTHYLSSSGVLPYLSKLGFEIVGYGCSTCVGNTAPLSEAILNA 596

  Fly   468 VKKGDKNTI-VTSYNRNFTGRNDANPATHC----FVTSPELVTALSIAG--RLDF--NPLTDELT 523
            ||:||..|. |.|.|:||.||     ...|    ::.||.||.|.:|||  .:||  .||..:.|
  Rat   597 VKQGDLVTCGVLSGNKNFEGR-----LCDCVRANYLASPPLVVAYAIAGTVNIDFQTEPLGTDST 656

  Fly   524 GAD-------------------------GKKFKLKAPFGDELPAKGFDPGQDTYTAPPPSGENVK 563
            |.:                         .|..|.|...|::        ..::..||    ::|.
  Rat   657 GKNIYLHDIWPSREEVHQIEEEHVILSMFKALKEKVEMGNK--------RWNSLDAP----DSVL 709

  Fly   564 VAVDPKSTRLQLLEPFDKWN-----GQDLTDLTVLIKVKGKCTTDHISAAGPWLKYRGHLDNISN 623
            ...|.|||.::....|||..     .|.:.:..||:.:....||||||.||...:.......::|
  Rat   710 FPWDVKSTYIRCPSFFDKLTKEPAASQPIENAHVLLYLGDSVTTDHISPAGSIARSSAAAKYLTN 774

  Fly   624 NMFIGATNYENNEMN---------------NIK--------------NQRNGSWGGVPDVARDYK 659
            .   |.|..|.|...               |||              :..:|....|.:.|..|:
  Rat   775 R---GLTPREFNSYGARRGNDAVMTRGTFANIKLFNKFIGKPAPKTIHFPSGQTLDVFEAAELYQ 836

  Fly   660 ANGIKWVAVGDENYGEGSSREHAALEPRHLGGRAIIVKSFARIHETNLKKQGLLPLTFANPADYD 724
            ..||..:.:..:.||.|:||:.||..|..||.:|::.:|:.:||:.:|...|:.||.|....:.|
  Rat   837 KEGIPLIILAGKKYGSGNSRDWAAKGPYLLGVKAVLAESYEKIHKDHLIGIGIAPLEFLPGENAD 901

  Fly   725 KIQPTSK--ISLLNLKSLAPGKPVDAEIKNGDKVERIKLNHTLNDLQIGWFKAGSALN 780
            .:..:.:  .||...:.|.||..::.:...|.:...|....  ||::|..:|.|..||
  Rat   902 SLGLSGREVFSLSFPEELFPGITLNIKTSTGKEFSVIAAFE--NDVEITLYKHGGLLN 957

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mAcon1	NP_001097186.2	aconitase_mito	52..782	CDD:273561	232/950 (24%)
		AcnA_Mitochondrial	102..513	CDD:153134	142/568 (25%)
		AcnA_Mitochon_Swivel	595..743	CDD:238810	45/178 (25%)
Ireb2	XP_038938018.1	PTZ00092	6..962	CDD:240263	237/968 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1048
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D190960at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.820