Protein Alignment mAcon1 and aco1

DIOPT Version :9

• Sequence 1: NP_001097186.2
• Gene: mAcon1 / 44149
• FlyBaseID: FBgn0010100
• Length: 787
• Species: Drosophila melanogaster
• Sequence 2: XP_012812984.1
• Gene: aco1 / 100216202
• XenbaseID: XB-GENE-1012108
• Length: 917
• Species: Xenopus tropicalis
• Alignment Length: 946
• Identity: 252/946 - (26%)
• Similarity: 384/946 - (40%)
• Gaps: 246/946 - (26%)

  Fly    17 KHVASEATVVRQFHASCYTASKVALSKFDSDVYLPY--------------EKLNKRLEVVRGRLN 67
            :|:|......:| ....|..:|:..|::   ..||:              |.|.|:.: |...||
 Frog    30 QHLAEPLDPAQQ-DKKFYNLNKLGDSRY---ARLPFSIRVLLEAAIRNCDEFLVKKQD-VENILN 89

  Fly    68 RPLTLSEKVLYSHLDDPANQDIVRGTSYLRLRPDRVAMQDATAQMALLQF--ISSGLKKV-AVPS 129
            ..||..:.|                  .:..||.||.:||.|...|::.|  :...:|:: ..|.
 Frog    90 WKLTQHDNV------------------EVPFRPARVILQDFTGVPAVVDFAAMRDAVKRLGGDPQ 136

  Fly   130 TVH--C------DHLIEAQIGGPKD-LARAKDL----NKEVYDFLASTCAKYG------LGFWKP 175
            |::  |      ||.|:.......| |.:.::|    |:|.::||     |:|      :....|
 Frog   137 TINPVCPVDLVIDHSIQVDFNRRSDSLQKNQELEFERNRERFEFL-----KWGSQAFQNMRIIPP 196

  Fly   176 GSGIIHQIILE----------NYAFPGLLMIGTDSHTPNGGGLGGLCIGVGGADAVDVMADIPWE 230
            |||||||:.||          .|.:|..| :||||||....|||.|..||||.:|..||...|..
 Frog   197 GSGIIHQVNLEYLARVVFDQDGYYYPDSL-VGTDSHTTMIDGLGVLGWGVGGIEAEAVMLGQPIS 260

  Fly   231 LKCPKVIGVNLTGKISGWTSPKDVILKVADILTVKGGTGAIIEYHGKGVDSISCTGMATICNMGA 295
            :..|:|||..|.|......:..|::|.|...|...|..|..:|:.|.||..:|....|||.||..
 Frog   261 MVLPEVIGYKLMGNPHPLVTSTDIVLTVTKHLRQVGVVGKFVEFFGTGVAQLSIADRATIANMCP 325

  Fly   296 EIGATTSLFPFNQRMADYLKSTGRAGIASEAQKYQAKILSA----------DKNCEYDELIEINL 350
            |.|||.:.||.:.....||:.|||   |.|..:|..|.|.|          :::.::.:::|::|
 Frog   326 EYGATAAFFPVDLVSVQYLQQTGR---AEEKVQYIQKYLEAAGLFRDFNNTNQDPDFSQVVELDL 387

  Fly   351 DTLEPHVNGPFTPDLGHPISKL---------------------GENSKKNGYPMD---------- 384
            .|:.|..:||..|.....:|::                     |.:..|..:|.:
 Frog   388 STVVPCCSGPKRPQDKVSVSEMKSDFQNCLGAKQGFKGFQIPQGHHYDKVKFPYNNTEYELSHGS 452

  Fly   385 IRVGLIGSCTNSSYED-MGRCASIAKDAMSHGL--KSKIPFNVTPGSEQIRATIERDGISEVFDK 446
            :.:..|.||||:|... |.....:||.|:..||  |..|..:::|||..:...:...|:.....|
 Frog   453 VVIAAITSCTNTSNPSVMLGAGLLAKKAVEAGLCVKPYIKTSLSPGSGVVTFYLRDSGVQPYLSK 517

  Fly   447 FGGTVLANACGPCIGQWDR------KDVKKGDKNTI-VTSYNRNFTGRNDANPATHC-FVTSPEL 503
            .|..|:...|..|||....      :.:.:||...: |.|.||||.||  .:|.|.. ::.||.|
 Frog   518 LGFDVVGYGCMTCIGNSGPLPDPVVEAITQGDLVAVGVLSGNRNFEGR--VHPNTRANYLASPPL 580

  Fly   504 VTALSIAG--RLDFN-------------------PLTDELTGADGK-----KFK----------- 531
            |.|.:|||  |:||.                   |..||:...:.:     .||
 Frog   581 VIAYAIAGTIRIDFEKDPLGVNAEGKEIYLRDIWPTRDEIQAVERQYVIPGMFKEVYEKIEKVNE 645

  Fly   532 ----LKAPFGDELPAKGFDPGQDTYTAPPPSGENVKVAVDPKSTRLQLLEPFDKWNGQDLTDLTV 592
                ||||..:..|   :|| :.||...||..:::.:.:.|.               :.:||..|
 Frog   646 SWNDLKAPTDELYP---WDP-KSTYIKSPPFFDSLTMELQPP---------------KSITDAYV 691

  Fly   593 LIKVKGKCTTDHISAAG------PWLKY-------------------------RGHLDNIS-NNM 625
            |:.:....||||||.||      |..:|                         ||...||. .|.
 Frog   692 LLNLGDSVTTDHISPAGNIARNSPAARYLVNRGLTPREFNSYGSRRGNDAVMARGTFANIRLFNK 756

  Fly   626 FIGATN-----YENNEMNNIKNQRNGSWGGVPDVARDYKANGIKWVAVGDENYGEGSSREHAALE 685
            ||...:     :.:||..:|.           |.|..|:.:|...:.:..:.||.||||:.||..
 Frog   757 FINKQSPSTIYFPSNETLDIF-----------DAAERYQNDGHNLILLTGKEYGSGSSRDWAAKG 810

  Fly   686 PRHLGGRAIIVKSFARIHETNLKKQGLLPLTFANPADYDKI----QPTSKISLLNLKSLAPGKPV 746
            |...|.:|::.:|:.|||.:||...|::||.:......:.:    |....|.:...|.|.||..|
 Frog   811 PFLQGIKAVLAESYERIHRSNLVGMGIIPLQYLPGESAEALGLSGQERYTIVIPEEKDLRPGMNV 875

  Fly   747 DAEIKNGDKVERIKLNHTLNDLQIGWFKAGSALNRM 782
            :.::..|...|.|....|  |:::.:::.|..||.|
 Frog   876 EIKLDTGKSFEAIMRFDT--DVELTYYRNGGILNYM 909

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mAcon1	NP_001097186.2	aconitase_mito	52..782	CDD:273561	243/909 (27%)
		AcnA_Mitochondrial	102..513	CDD:153134	149/496 (30%)
		AcnA_Mitochon_Swivel	595..743	CDD:238810	48/188 (26%)
aco1	XP_012812984.1	PTZ00092	26..916	CDD:240263	252/946 (27%)
		AcnA_IRP	106..590	CDD:153136	149/494 (30%)
		AcnA_IRP_Swivel	694..863	CDD:238812	46/179 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D190960at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	2.010